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1. (WO2013116668) DIAGNOSTIC PEPTIDES FOR LYME DISEASE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2013/116668    International Application No.:    PCT/US2013/024370
Publication Date: 08.08.2013 International Filing Date: 01.02.2013
IPC:
A61K 39/02 (2006.01)
Applicants: BIOPEPTIDES CORP [US/US]; 18 Woodhull Road East Setauket, New York 11733 (US)
Inventors: DATTWYLER, Raymond, J.; (US).
ARNABOLDI, Paul, M.; (US)
Agent: AXELROD, Nancy, J.; Venable LLP P.O. Box 34385 Washington, DC 20043-9998 (US)
Priority Data:
61/593,605 01.02.2012 US
61/680,583 07.08.2012 US
61/705,344 25.09.2012 US
Title (EN) DIAGNOSTIC PEPTIDES FOR LYME DISEASE
(FR) PEPTIDES DIAGNOSTIQUES POUR LA MALADIE DE LYME
Abstract: front page image
(EN)The present invention relates, e.g., to a composition comprising peptides represented by SEQ ID NO:1 - SEQ ID NO:28 or SEQ ID NO:41-SEQ ID NO:47, or active variants thereof, wherein the peptides or active variants can bind specifically to an antibody induced by a causative agent of Lyme disease (a pathogenic Borrelia), e.g. in a sample from a subject having Lyme disease. Compositions of the invention may comprise multiple peptides, from multiple proteins. Diagnostic kits comprising the peptides are described, as are diagnostic assays using the peptides.
(FR)La présente invention concerne par exemple une composition comprenant des peptides représentés par la SEQ ID n° 1 - SEQ ID n°28 ou SEQ ID n°41-SEQ ID n° 47, ou leurs variants actifs, les peptides ou leurs variants actifs pouvant se lier spécifiquement à un anticorps induit par un agent pathogène de la maladie de Lyme (Borrelia pathogène), par ex. dans un échantillon issu d'un sujet présentant la maladie de Lyme. Les compositions de l'invention peuvent comprendre plusieurs peptides, issus de plusieurs protéines. L'invention concerne des kits de diagnostic comprenant lesdits peptides ainsi que des dosages diagnostiques utilisant lesdits peptides.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)