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1. (WO2013116663) NOVEL CYSTEINE PROTEASE INHIBITORS AND USES THEREOF

Pub. No.:    WO/2013/116663    International Application No.:    PCT/US2013/024364
Publication Date: Fri Aug 09 01:59:59 CEST 2013 International Filing Date: Sat Feb 02 00:59:59 CET 2013
IPC: A61K 31/427
Applicants: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS
Inventors: THATCHER, Greg, R.
SCHIEFER, Isaac, Thomas
ARANCIO, Ottavio
FA, Mauro
Title: NOVEL CYSTEINE PROTEASE INHIBITORS AND USES THEREOF
Abstract:
The invention provides for novel cysteine protease inh ibitors and compositions comprising novel cysteine protease derivatives. The invention further provides for methods for treatment of neurodegenerative diseases comprising administration novel cysteine protease inhibitors or compositions comprising novel cysteine protease inhibitors. In some embodiments, the cysteine protease inhibitors are calpain inhibitors.