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1. (WO2013116663) NOVEL CYSTEINE PROTEASE INHIBITORS AND USES THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2013/116663    International Application No.:    PCT/US2013/024364
Publication Date: 08.08.2013 International Filing Date: 01.02.2013
IPC:
A61K 31/427 (2006.01)
Applicants: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK [US/US]; 412 Low Memorial Library 535 West 116th Street New York, NY 10027 (US).
THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS [US/US]; 352 Henry Administration Building 506 S. Wright Street Urbana, Illinois 61801 (US)
Inventors: THATCHER, Greg, R.; (US).
SCHIEFER, Isaac, Thomas; (US).
ARANCIO, Ottavio; (US).
FA, Mauro; (US)
Agent: BAIK, Peter, W.; Wilmer Cutler Pickering Hale And Dorr LLP 7 World Trade Center 250 Greenwich Street New York, NY 10007 (US)
Priority Data:
61/593,664 01.02.2012 US
Title (EN) NOVEL CYSTEINE PROTEASE INHIBITORS AND USES THEREOF
(FR) NOUVEAUX INHIBITEURS DE PROTÉASES À CYSTÉINE ET LEURS UTILISATIONS
Abstract: front page image
(EN)The invention provides for novel cysteine protease inh ibitors and compositions comprising novel cysteine protease derivatives. The invention further provides for methods for treatment of neurodegenerative diseases comprising administration novel cysteine protease inhibitors or compositions comprising novel cysteine protease inhibitors. In some embodiments, the cysteine protease inhibitors are calpain inhibitors.
(FR)L'invention concerne de nouveaux inhibiteurs de protéases à cystéine et des compositions comportant de nouveaux dérivés de protéases à cystéine. L'invention concerne en outre des méthodes de traitement de maladies neurodégénératives qui comportent l'administration de nouveaux inhibiteurs de protéases à cystéine ou des compositions comportant de nouveaux inhibiteurs de protéases à cystéine. Dans certains modes de réalisation, les inhibiteurs de protéases à cystéine sont des inhibiteurs de la calpaïne.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)