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1. (WO2013116523) CIRCULATING TUMOR CELL CAPTURING TECHNIQUES AND DEVICES
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2013/116523 International Application No.: PCT/US2013/024150
Publication Date: 08.08.2013 International Filing Date: 31.01.2013
IPC:
G01N 33/543 (2006.01) ,G01N 15/14 (2006.01)
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
543
with an insoluble carrier for immobilising immunochemicals
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
15
Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
10
Investigating individual particles
14
Electro-optical investigation
Applicants: BERSANO-BEGEY, Tommaso, F.[US/US]; US (AllExceptUS)
HAYES, Daniel, F.[US/US]; US (AllExceptUS)
THE REGENTS OF THE UNIVERSITY OF MICHIGAN[US/US]; Office of Technology Transfer 1600 Huron Parkway, 2nd Floor Ann Arbor, MI 48109-2590, US
Inventors: BERSANO-BEGEY, Tommaso, F.; US
HAYES, Daniel, F.; US
Agent: STEPHENS, Paul, B.; Marshall, Gerstein & Borun LLP 233 S. Wacker Drive 6300 Willis Tower Chicago, IL 60606-6357, US
Priority Data:
61/593,09231.01.2012US
Title (EN) CIRCULATING TUMOR CELL CAPTURING TECHNIQUES AND DEVICES
(FR) TECHNIQUES ET DISPOSITIFS DE CAPTURE DE CELLULES TUMORALES CIRCULANTES
Abstract:
(EN) Candidate cells, such as circulating tumor cells (CTCs), present with blood are captured using a multiple stage device, having successive stages configured to deviate candidate cells out of the blood while slowing down the flow rates of the deviated resultant for easier capture of CTCs through progressive stages. The devices can include separation channel and deviation channels formed of micro-post patterns dimensioned to deviate different desired candidate cells for analysis.
(FR) Des cellules candidates, telles que des cellules tumorales circulantes (CTC), présentes avec le sang sont capturées à l'aide d'un dispositif à étages multiples, avec des étages successifs configurés pour dévier des cellules candidates hors du sang tout en ralentissant les débits de la résultante déviée pour faciliter la capture de cellules tumorales circulantes (CTC) par l'intermédiaire d'étages progressifs. Les dispositifs peuvent comprendre un canal de séparation et des canaux de déviation formés de motifs de micro-tige dimensionnés de manière à dévier différentes cellules candidates souhaitées pour l'analyse.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)