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1. (WO2013116523) CIRCULATING TUMOR CELL CAPTURING TECHNIQUES AND DEVICES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2013/116523    International Application No.:    PCT/US2013/024150
Publication Date: 08.08.2013 International Filing Date: 31.01.2013
IPC:
G01N 33/543 (2006.01), G01N 15/14 (2006.01)
Applicants: THE REGENTS OF THE UNIVERSITY OF MICHIGAN [US/US]; Office of Technology Transfer 1600 Huron Parkway, 2nd Floor Ann Arbor, MI 48109-2590 (US).
BERSANO-BEGEY, Tommaso, F. [US/US]; (US) (For All Designated States Except US).
HAYES, Daniel, F. [US/US]; (US) (For All Designated States Except US)
Inventors: BERSANO-BEGEY, Tommaso, F.; (US).
HAYES, Daniel, F.; (US)
Agent: STEPHENS, Paul, B.; Marshall, Gerstein & Borun LLP 233 S. Wacker Drive 6300 Willis Tower Chicago, IL 60606-6357 (US)
Priority Data:
61/593,092 31.01.2012 US
Title (EN) CIRCULATING TUMOR CELL CAPTURING TECHNIQUES AND DEVICES
(FR) TECHNIQUES ET DISPOSITIFS DE CAPTURE DE CELLULES TUMORALES CIRCULANTES
Abstract: front page image
(EN)Candidate cells, such as circulating tumor cells (CTCs), present with blood are captured using a multiple stage device, having successive stages configured to deviate candidate cells out of the blood while slowing down the flow rates of the deviated resultant for easier capture of CTCs through progressive stages. The devices can include separation channel and deviation channels formed of micro-post patterns dimensioned to deviate different desired candidate cells for analysis.
(FR)Des cellules candidates, telles que des cellules tumorales circulantes (CTC), présentes avec le sang sont capturées à l'aide d'un dispositif à étages multiples, avec des étages successifs configurés pour dévier des cellules candidates hors du sang tout en ralentissant les débits de la résultante déviée pour faciliter la capture de cellules tumorales circulantes (CTC) par l'intermédiaire d'étages progressifs. Les dispositifs peuvent comprendre un canal de séparation et des canaux de déviation formés de motifs de micro-tige dimensionnés de manière à dévier différentes cellules candidates souhaitées pour l'analyse.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)