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1. (WO2013116375) MODIFICATION OF DNA ON MAGNETIC BEADS

Pub. No.:    WO/2013/116375    International Application No.:    PCT/US2013/023908
Publication Date: Fri Aug 09 01:59:59 CEST 2013 International Filing Date: Thu Jan 31 00:59:59 CET 2013
IPC: C12Q 1/68
Applicants: EXACT SCIENCES CORPORATION
Inventors: DOMANICO, Michael J.
ALLAWI, Hatim
LIDGARD, Graham P.
AIZENSTEIN, Brian
HUNT, Oliver
ZUTZ, Tobias Charles
Title: MODIFICATION OF DNA ON MAGNETIC BEADS
Abstract:
Provided herein is technology related to the chemical modification and purification of DNA. Specifically, the technology provides methods for performing a bisulfite conversion reaction on small amounts of single-stranded, fragmented DNA and performing the subsequent desulfonation and purification steps on magnetic beads.