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1. (WO2013116375) MODIFICATION OF DNA ON MAGNETIC BEADS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2013/116375    International Application No.:    PCT/US2013/023908
Publication Date: 08.08.2013 International Filing Date: 30.01.2013
IPC:
C12Q 1/68 (2006.01)
Applicants: EXACT SCIENCES CORPORATION [US/US]; 441 Charmany Drive Madison, Wisconsin 53719 (US)
Inventors: DOMANICO, Michael J.; (US).
ALLAWI, Hatim; (US).
LIDGARD, Graham P.; (US).
AIZENSTEIN, Brian; (US).
HUNT, Oliver; (US).
ZUTZ, Tobias Charles; (US)
Agent: BROW, Mary Ann D.; 2275 Deming Way, Suite 310 Middleton, Wisconsin 53562 (US)
Priority Data:
61/592,272 30.01.2012 US
Title (EN) MODIFICATION OF DNA ON MAGNETIC BEADS
(FR) MODIFICATION D'ADN SUR DES BILLES MAGNÉTIQUES
Abstract: front page image
(EN)Provided herein is technology related to the chemical modification and purification of DNA. Specifically, the technology provides methods for performing a bisulfite conversion reaction on small amounts of single-stranded, fragmented DNA and performing the subsequent desulfonation and purification steps on magnetic beads.
(FR)La présente invention concerne une technologie associée à la modification et à la purification chimiques d'ADN. Plus particulièrement, la technologie fournit des procédés destinés à exécuter une réaction de conversion de bisulfite sur de petites quantités d'ADN fragmenté à un seul brin et à exécuter les étapes de désulfonation et de purification ultérieures sur des billes magnétiques.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)