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1. (WO2013114372) METHOD FOR INDUCING IMMUNE TOLERANCE TO ORGAN TRANSPLANTS

Pub. No.:    WO/2013/114372    International Application No.:    PCT/IL2013/050095
Publication Date: Fri Aug 09 01:59:59 CEST 2013 International Filing Date: Fri Feb 01 00:59:59 CET 2013
IPC: A01N 1/02
A61B 5/00
A61B 17/00
A61L 33/00
A61L 27/36
Applicants: NAYACURE THERAPEUTICS LTD.
Inventors: COHEN, Shahar
Title: METHOD FOR INDUCING IMMUNE TOLERANCE TO ORGAN TRANSPLANTS
Abstract:
The present invention is directed to methods of treating an organ or a tissue prior to transplantation thereof into a recipient, comprising ablating the cells composing the blood vessels of said organ or tissue, preferably the cells lining the lumen surface of the blood vessels, thereby obtaining a treated viable organ or tissue having reduced immunogenicity. The invention is also directed to treated viable organs or tissues having reduced immunogenicity and uses thereof.