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1. (WO2013114180) CYCLIC PEPTIDE INTEGRIN DERIVATIVES FOR USE AS ANTICANCER AGENTS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2013/114180    International Application No.:    PCT/IB2013/000116
Publication Date: 08.08.2013 International Filing Date: 30.01.2013
IPC:
C07K 5/02 (2006.01), A61P 35/00 (2006.01)
Applicants: UNIVERSITA' DEGLI STUDI DI MILANO [IT/IT]; Via Festa del Perdono, 7 I-20122 Milano (IT).
FONDAZIONE IRCCS ISTITUTO NAZIONALE DEI TUMORI DI MILANO [IT/IT]; Via Venezian, 1 I-20133 Milan (IT).
UNIVERSITA' DEGLI STUDI DELL'INSUBRIA [IT/IT]; Via Ravasi, 2 I-21100 Varese (IT)
Inventors: GENNARI, Cesare, Mario, Arturo; (IT).
BELVISI, Laura; (IT).
POTENZA, Donatella; (IT).
COLOMBO, Raffaele; (IT).
MINGOZZI, Michele; (IT).
MARCHINI, Mattia; (IT).
MANZONI, Leonardo, Pierpaolo; (IT).
AROSIO, Daniela; (IT).
PEREGO, Paola, Maria, Chiara; (IT).
ZAFFARONI, Nadia; (IT).
DE CESARE, Michelandrea; (IT).
PIARULLI, Umberto; (IT)
Agent: TRUPIANO, Federica; Marietti, Gislon e Trupiano S.r.l. Via Larga, 16 I-20122 Milano (IT)
Priority Data:
MI2012A000121 31.01.2012 IT
Title (EN) CYCLIC PEPTIDE INTEGRIN DERIVATIVES FOR USE AS ANTICANCER AGENTS
(FR) DÉRIVÉS PEPTIDIQUES CYCLIQUES DE L'INTÉGRINE DESTINÉS À ÊTRE UTILISÉS COMME AGENTS ANTICANCÉREUX
Abstract: front page image
(EN)The present invention has as an object new anticancer compounds of formula (I), in particular conjugates between cytotoxic entities and peptidomimetic type integrin ligands. The invention has also as an object a process for their preparation and their use for anticancer therapy.
(FR)La présente invention concerne de nouveaux composés anticancéreux de formule (I), en particulier des conjugués entre des entités cytotoxiques et des ligands d'intégrine de type peptidomimétique. L'invention concerne également un procédé pour leur préparation et leur utilisation dans le cadre d'une thérapie anticancéreuse. (I).
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: Italian (IT)