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1. (WO2013113941) CD8+T-CELL SUBSETS AS MARKERS FOR PREDICTION OF DELAYED FRACTURE HEALING

Pub. No.:    WO/2013/113941    International Application No.:    PCT/EP2013/052181
Publication Date: Fri Aug 09 01:59:59 CEST 2013 International Filing Date: Tue Feb 05 00:59:59 CET 2013
IPC: G01N 33/50
Applicants: CHARITÈ UNIVERSITÄTSMEDIZIN BERLIN
Inventors: DUDA, Georg
VOLK, Hans-Dieter
REINKE, Simon
MEISEL, Christian
KLEBER, Christian
GEISSLER, Sven
SCHMIDT-BLEEK, Katharina
Title: CD8+T-CELL SUBSETS AS MARKERS FOR PREDICTION OF DELAYED FRACTURE HEALING
Abstract:
ipa105wo 32 Abstract The present invention relates to a method for diagnosis of delayed bone fracture healing, comprising determining the frequency of a subpopulation of CD8+ cells selected from a first group comprised of CD8+CD57+, CD8+CD28- and CD8+CD28-/CD57+, in a sample obtained from a subject. The present invention further relates to a system and a kit of parts for prediction and resulting options for preventing of delayed bone fracture healing.