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1. (WO2013113774) FACTOR XII INHIBITORS FOR THE TREATMENT OF NEUROLOGICAL INFLAMMATORY DISORDERS
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2013/113774 International Application No.: PCT/EP2013/051832
Publication Date: 08.08.2013 International Filing Date: 31.01.2013
IPC:
A61K 38/06 (2006.01) ,A61K 38/48 (2006.01) ,A61K 38/55 (2006.01) ,A61K 38/57 (2006.01) ,A61K 39/395 (2006.01) ,A61K 47/48 (2006.01) ,A61P 25/00 (2006.01) ,A61P 37/00 (2006.01) ,C07K 14/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
04
Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
06
Tripeptides
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
43
Enzymes; Proenzymes; Derivatives thereof
46
Hydrolases (3)
48
acting on peptide bonds (3.4)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
55
Protease inhibitors
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
55
Protease inhibitors
57
from animals; from humans
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
395
Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
48
the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25
Drugs for disorders of the nervous system
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
37
Drugs for immunological or allergic disorders
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
Applicants: CSL BEHRING GMBH[DE/DE]; Emil-von-Behring-Strasse 76 35041 Marburg, DE
CSL LTD.[AU/AU]; 45 Poplar Road Parkville, Victoria 3052, AU
JULIUS-MAXIMILIANS-UNIVERSITAET-WUERZBURG[DE/DE]; Sanderring 2 Wuerzburg, 97070, DE
WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER[DE/DE]; Schlossplatz 2 48149 Muenster, DE
Inventors: MEUTH, Sven; DE
GOEBEL, Kerstin; DE
KLEINSCHNITZ, Christoph; DE
MCKENZIE, Brent; US
NOLTE, Marc; DE
Agent: BINSACK, Beate; CSL Behring GmbH Emil-von-Behring-Straße 76 35041 Marburg, DE
Priority Data:
12153341.831.01.2012EP
61/592,65231.01.2012US
Title (EN) FACTOR XII INHIBITORS FOR THE TREATMENT OF NEUROLOGICAL INFLAMMATORY DISORDERS
(FR) INHIBITEURS DU FACTEUR XII DESTINÉS AU TRAITEMENT DE TROUBLES INFLAMMATOIRES NEUROLOGIQUES
Abstract:
(EN) This application relates to neurological inflammatory diseases, such as multiple sclerosis, and to methods of administering a Factor XII inhibitor to prevent, treat, or otherwise ameliorate the effects of a neurological inflammatory disease, such as multiple sclerosis. Agents and pharmaceutical compositions comprising agents which inhibit the activity of FXII are also provided.
(FR) La présente invention concerne des maladies inflammatoires neurologiques, telles que la sclérose en plaques, et des procédés d'administration d'un inhibiteur du facteur XII pour prévenir, traiter ou améliorer autrement les effets d'une maladie inflammatoire neurologique, telle que la sclérose en plaques. Des agents et des compositions pharmaceutiques comprenant des agents inhibant l'activité du FXII sont également décrits.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)