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1. (WO2013113689) EXPRESSION METHOD
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2013/113689 International Application No.: PCT/EP2013/051656
Publication Date: 08.08.2013 International Filing Date: 29.01.2013
IPC:
C12R 1/07 (2006.01) ,C12N 15/75 (2006.01) ,C12P 1/04 (2006.01)
Applicants: BASF SE[DE/DE]; 67056 Ludwigshafen, DE
Inventors: KÜPPERS, Tobias; DE
STEFFEN, Victoria; DE
EICHSTÄDT, Renée, Charlott; DE
EVERS, Stefan; DE
MAURER, Karl-Heinz; DE
BONGAERTS, Johannes; DE
HELLMUTH, Hendrik; DE
WEBER, Thomas; DE
O'CONNELL, Timothy; DE
Agent: NEUEFEIND, Regina; Maiwald Patentanwalts GmbH Elisenhof, Elisenstrasse 3 80335 München, DE
Priority Data:
10 2012 201 297.431.01.2012DE
Title (EN) EXPRESSION METHOD
(FR) PROCÉDÉ D'EXPRESSION
(DE) EXPRESSIONSVERFAHREN
Abstract:
(EN) The aim of the invention is to increase the product yield of protein in a microbial fermentation process. Said aim is achieved by means of a method in which an expression construct is introduced into a microorganism of the species Bacillus pumilus, which expression construct comprises a promoter and a nucleic acid that codes for the protein, and the protein is expressed in said expression construct.
(FR) L'invention a pour but d'augmenter le rendement en protéines produites dans une fermentation microbienne. Ce but est atteint par le biais d'un procédé comprenant l'introduction d'un vecteur d'expression, lequel contient un promoteur et un acide nucléique codant pour la protéine, dans un micro-organisme du type Bacillus pumilus, et l'expression de la protéine dans ledit micro-organisme.
(DE) In einer mikrobiellen Fermentation soll die Produktausbeute an Protein erhöht werden. Dies gelingt durch ein Verfahren, bei dem ein Expressionskonstrukt in einen Mikroorganismus der Art Bacillus pumilus eingebracht wird, welches einen Promotor und eine für das Protein codierende Nukleinsäure umfasst und das Protein in diesem exprimiert wird.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: German (DE)
Filing Language: German (DE)