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1. (WO2013112743) BIOMIMETIC SURFACES FOR ENHANCING MUSCULOSKELETAL REGENERATION

Pub. No.:    WO/2013/112743    International Application No.:    PCT/US2013/022999
Publication Date: Fri Aug 02 01:59:59 CEST 2013 International Filing Date: Fri Jan 25 00:59:59 CET 2013
IPC: A61L 27/02
A61L 27/42
A61F 2/28
Applicants: THE PENN STATE RESEARCH FOUNDATION
LAKHTAKIA, Akhlesh
DONAHUE, Henry, J.
Inventors: LAKHTAKIA, Akhlesh
DONAHUE, Henry, J.
Title: BIOMIMETIC SURFACES FOR ENHANCING MUSCULOSKELETAL REGENERATION
Abstract:
Bone transplant compositions, soft musculoskeletal tissue implants, and orthopedic device implants are provided according to the present invention which include an exterior surface, the exterior surface at least partially coated with an applied hydroxyapatite coating, the applied hydroxyapatite coating characterized by an average overall thickness in the range of 45-70 nm, inclusive, more preferably 48-65 nm, inclusive, and still more preferably, 50-60 nm, inclusive. Methods of production and use of bone transplant compositions, soft musculoskeletal tissue implants, and orthopedic device implants according to the present invention are provided herein.