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1. (WO2013112528) METHODS AND COMPOSITIONS RELATING TO PROLIFERATIVE DISORDERS OF THE PROSTATE

Pub. No.:    WO/2013/112528    International Application No.:    PCT/US2013/022667
Publication Date: Fri Aug 02 01:59:59 CEST 2013 International Filing Date: Thu Jan 24 00:59:59 CET 2013
IPC: C12Q 1/26
C12N 9/02
G01N 33/574
G01N 33/53
Applicants: WEST CHESTER UNIVERSITY OF PENNSYLVANIA
BADER-SLUSHER, Leslie
BENESKI, John, T., Jr.
Inventors: BADER-SLUSHER, Leslie
BENESKI, John, T., Jr.
Title: METHODS AND COMPOSITIONS RELATING TO PROLIFERATIVE DISORDERS OF THE PROSTATE
Abstract:
Methods and kits for aiding in detection, assessment and treatment of a proliferative disorder of the prostate gland in a subject are provided according to aspects of the present invention which include assaying a first biological sample comprising prostate gland cells obtained from the subject for expression of one or more biomarkers selected from the group consisting of: alcohol dehydrogenase 1B, alcohol dehydrogenase 1C, alcohol dehydrogenase 4 and hepatocyte nuclear factor 1B; and determining, based on the expression of the one or more biomarkers in the sample that the subject has, or is at risk of having, a proliferative disorder of the prostate gland.