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1. (WO2013111909) METHOD FOR SCREENING FOR Nrf1 REGULATOR
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2013/111909    International Application No.:    PCT/JP2013/051941
Publication Date: 01.08.2013 International Filing Date: 23.01.2013
IPC:
C12Q 1/02 (2006.01), C12Q 1/68 (2006.01), G01N 33/15 (2006.01), G01N 33/50 (2006.01), G01N 33/68 (2006.01), C12N 15/09 (2006.01)
Applicants: MOCHIDA PHARMACEUTICAL CO., LTD. [JP/JP]; 7, Yotsuya 1-chome, Shinjuku-ku, Tokyo 1608515 (JP).
TOHOKU UNIVERSITY [JP/JP]; 1-1, Katahira 2-chome, Aoba-ku, Sendai-shi, Miyagi 9808577 (JP)
Inventors: YAMAMOTO, Masayuki; (JP).
FURUSAWA, Yuki; (JP)
Agent: KOBAYASHI, Hiroshi; ABE, IKUBO & KATAYAMA, Fukuoka Bldg. 9th Fl., 8-7, Yaesu 2-chome, Chuo-ku, Tokyo 1040028 (JP)
Priority Data:
2012-011833 24.01.2012 JP
Title (EN) METHOD FOR SCREENING FOR Nrf1 REGULATOR
(FR) PROCÉDÉ DE CRIBLAGE DE RÉGULATEURS DE Nrf1
(JA) Nrf1調節剤のスクリーニング方法
Abstract: front page image
(EN)The invention provides a method for the screening of compounds that regulate Nrf1 activity from among sample compounds, said method using Nrf1 and Lipin1 and/or PGC-1β. The invention provides a method for the screening of compounds that regulate Nrf1 activity.
(FR)L'invention concerne un procédé de criblage de composés qui régulent l'activité de Nrf1 à partir de composés d'échantillons, ledit procédé utilisant Nrf1 et Lipin1 et/ou PGC-1β. L'invention concerne un procédé de criblage de composés qui régulent l'activité de Nrf1.
(JA) 本発明は、Nrf1とLipin1および/またはPGC-1βとを用いることを含む、試験化合物からNrf1の活性を調節する化合物をスクリーニングする方法を提供する。本発明により、Nrf1の活性を調節する化合物をスクリーニングする方法が提供される。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)