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1. (WO2013111105) IMIDAZOPYRROLIDINONE COMPOUNDS

Pub. No.:    WO/2013/111105    International Application No.:    PCT/IB2013/050655
Publication Date: Fri Aug 02 01:59:59 CEST 2013 International Filing Date: Sat Jan 26 00:59:59 CET 2013
IPC: C07D 487/04
A61K 31/4188
A61P 35/00
Applicants: NOVARTIS AG
Inventors: FURET, Pascal
GUAGNANO, Vito
HOLZER, Philipp
KALLEN, Joerg
LIAO, Lv
MAH, Robert
MAO, Liang
MASUYA, Keiichi
SCHLAPBACH, Achim
STUTZ, Stefan
VAUPEL, Andrea
Title: IMIDAZOPYRROLIDINONE COMPOUNDS
Abstract:
The invention relates to compounds of formula (I): (I) as described herein, pharmaceutical preparations comprising such compounds, uses and methods of use for such compounds in the treatment of a disorder or a disease mediated by the activity of MDM2 and/or MDM4, and combinations comprising such compounds.