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1. (WO2013110458) METHOD FOR DEMONSTRATING FLAWS IN AN ULTRAFILTRATION MEMBRANE

Pub. No.:    WO/2013/110458    International Application No.:    PCT/EP2013/000205
Publication Date: Fri Aug 02 01:59:59 CEST 2013 International Filing Date: Thu Jan 24 00:59:59 CET 2013
IPC: B01D 65/10
Applicants: SARTORIUS STEDIM BIOTECH GMBH
Inventors: DEMMER, Wolfgang
HÖRL, Hans-Heinrich
VILLAIN, Louis
SCHREIBER, Tony
Title: METHOD FOR DEMONSTRATING FLAWS IN AN ULTRAFILTRATION MEMBRANE
Abstract:
The present invention relates to a method for demonstrating flaws in an ultrafiltration membrane (1), comprising the steps: (a) preparing an aqueous solution (2) containing a substance to which a dye is bound; (b) providing an arrangement of a filtration module (A, B) with an ultrafiltration membrane (1); and (c) applying the aqueous solution (2) that was prepared in step (a) to the ultrafiltration membrane (1), so that the aqueous solution (2) is subjected to an ultrafiltration, wherein if at least one flaw (4) is present in the ultrafiltration membrane (1), the substance to which a dye is bound passes through the at least one flaw (4) of the ultrafiltration membrane (1) and appears there optically due to colouration, the size of the substance in the aqueous solution (2) being selected in such a way that an ultrafiltration membrane (1) without flaws is not permeable for the substance with a dye bound thereto, wherein the arrangement in step (b) is further provided with a microporous membrane adsorber (3) in such a way that the surface of the ultrafiltration membrane (1) facing a filtrate space (B) of the filtration module (A, B) is in full-surface contact with a surface (31) of the membrane adsorber (3) and in step (c) the substance to which a dye is bound is adsorbed on the membrane adsorber (3) after passage through the at least one flaw (4) of the ultrafiltration membrane (1).