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1. WO2013109735 - TRICYCLIC SULFONE COMPOUNDS AND METHODS OF MAKING AND USING SAME

Publication Number WO/2013/109735
Publication Date 25.07.2013
International Application No. PCT/US2013/021914
International Filing Date 17.01.2013
IPC
C07D 311/78 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
311Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
02ortho- or peri-condensed with carbocyclic rings or ring systems
78Ring systems having three or more relevant rings
A61K 31/353 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
335having oxygen as the only ring hetero atom, e.g. fungichromin
35having six-membered rings with one oxygen as the only ring hetero atom
352condensed with carbocyclic rings, e.g. cannabinols, methantheline
3533,4-Dihydrobenzopyrans, e.g. chroman, catechin
A61P 3/04 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3Drugs for disorders of the metabolism
04Anorexiants; Antiobesity agents
CPC
A61P 3/04
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3Drugs for disorders of the metabolism
04Anorexiants; Antiobesity agents
A61P 9/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
9Drugs for disorders of the cardiovascular system
C07D 311/94
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
311Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
02ortho- or peri-condensed with carbocyclic rings or ring systems
94condensed with rings other than six-membered
Applicants
  • ZAFGEN, INC. [US]/[US]
Inventors
  • PALLIN, Thomas, David
  • DYKE, Hazel, Joan
  • CRAMP, Susan, Mary
  • ZAHLER, Robert
Agents
  • KAVANAUGH, Theresa, C.
Priority Data
61/587,82518.01.2012US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) TRICYCLIC SULFONE COMPOUNDS AND METHODS OF MAKING AND USING SAME
(FR) COMPOSÉS SULFONES TRICYCLIQUES ET LEURS PROCÉDÉS DE FABRICATION ET D'UTILISATION
Abstract
(EN) The invention provides tricyclic sulfone compounds and their use in treating medical disorders, such as obesity. Pharmaceutical compositions and methods of making various tricyclic compounds are provided. The compounds are contemplated to have activity against methionyl aminopeptidase 2.
(FR) L'invention concerne des composés sulfones tricycliques et leur utilisation dans le traitement de troubles médicaux, tels que l'obésité. L'invention concerne également des compositions pharmaceutiques et des procédés de fabrication de divers composés tricycliques. Il est envisagé que les composés ont une activité contre la méthionyl aminopeptidase 2.
Related patent documents
MXMX/a/2014/008705This application is not viewable in PATENTSCOPE because the national phase entry has not been published yet or the national entry is issued from a country that does not share data with WIPO or there is a formatting issue or an unavailability of the application.
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