Processing

Please wait...

Settings

Settings

1. WO2013102142 - SUBSTITUTED BENZALDEHYDE COMPOUNDS AND METHODS FOR THEIR USE IN INCREASING TISSUE OXYGENATION

Publication Number WO/2013/102142
Publication Date 04.07.2013
International Application No. PCT/US2012/072177
International Filing Date 28.12.2012
IPC
A HUMAN NECESSITIES
01
AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
N
PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
35
Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having two bonds to hetero atoms with at the most one bond to halogen, e.g. aldehyde radical
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
11
Aldehydes
A01N 35/00 (2006.01)
A61K 31/11 (2006.01)
CPC
A61K 31/192
A61K 31/235
A61K 31/41
A61K 31/416
A61K 31/437
A61K 31/4406
Applicants
  • GLOBAL BLOOD THERAPEUTICS, INC. [US/US]; 29 Newbury Street Boston, Massachusetts 02116, US
  • CYTOKINETICS, INC. [US/US]; 280 East Grand Avenue South San Francisco, California 94080, US
  • THE REGENTS OF THE UNIVERSITY OF CALIFORNIA [US/US]; 1111 Franklin Street 12th Floor Oakland, California 94607, US
Inventors
  • METCALF, Brian; US
  • CHUANG, Chihyuan; US
  • WARRINGTON, Jeffrey; US
  • PAULVANNAN, Kumar; US
  • JACOBSON, Matthew P.; US
  • HUA, Lan; US
  • MORGAN, Bradley; US
Agents
  • HOPKINS, Mark; Kilpatrick Townsend & Stockton LLP Two Embarcadero Center, Eighth Floor San Francisco, California 94111-3834, US
Priority Data
61/581,05328.12.2011US
61/661,32018.06.2012US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) SUBSTITUTED BENZALDEHYDE COMPOUNDS AND METHODS FOR THEIR USE IN INCREASING TISSUE OXYGENATION
(FR) COMPOSÉS BENZALDÉHYDE SUBSTITUÉS ET PROCÉDÉS D'UTILISATION DE CEUX-CI DANS L'AUGMENTATION DE L'OXYGÉNATION DES TISSUS
Abstract
(EN)
Provided are substituted benzaldehydes and derivatives thereof that act as allosteric modulators of hemoglobin, methods and intermediates for their preparation, pharmaceutical compositions comprising the modulators, and methods for their use in treating disorders mediate by hemoglobin and disorders that would benefit from increased tissue oxygenation.
(FR)
La présente invention concerne des benzaldéhydes substitués et des dérivés de ceux-ci qui agissent comme modulateurs allostériques de l'hémoglobine, des procédés et des intermédiaires dans la préparation de ceux-ci, des compositions pharmaceutiques comprenant les modulateurs, et des méthodes d'utilisation de celles-ci dans le traitement de troubles médiés par l'hémoglobine et de troubles qui pourraient bénéficier d'une oxygénation accrue des tissus.
Latest bibliographic data on file with the International Bureau