WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2013102142) SUBSTITUTED BENZALDEHYDE COMPOUNDS AND METHODS FOR THEIR USE IN INCREASING TISSUE OXYGENATION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2013/102142    International Application No.:    PCT/US2012/072177
Publication Date: 04.07.2013 International Filing Date: 28.12.2012
IPC:
A01N 35/00 (2006.01), A61K 31/11 (2006.01)
Applicants: GLOBAL BLOOD THERAPEUTICS, INC. [US/US]; 29 Newbury Street Boston, Massachusetts 02116 (US).
CYTOKINETICS, INC. [US/US]; 280 East Grand Avenue South San Francisco, California 94080 (US).
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA [US/US]; 1111 Franklin Street 12th Floor Oakland, California 94607 (US)
Inventors: METCALF, Brian; (US).
CHUANG, Chihyuan; (US).
WARRINGTON, Jeffrey; (US).
PAULVANNAN, Kumar; (US).
JACOBSON, Matthew P.; (US).
HUA, Lan; (US).
MORGAN, Bradley; (US)
Agent: HOPKINS, Mark; Kilpatrick Townsend & Stockton LLP Two Embarcadero Center, Eighth Floor San Francisco, California 94111-3834 (US)
Priority Data:
61/581,053 28.12.2011 US
61/661,320 18.06.2012 US
Title (EN) SUBSTITUTED BENZALDEHYDE COMPOUNDS AND METHODS FOR THEIR USE IN INCREASING TISSUE OXYGENATION
(FR) COMPOSÉS BENZALDÉHYDE SUBSTITUÉS ET PROCÉDÉS D'UTILISATION DE CEUX-CI DANS L'AUGMENTATION DE L'OXYGÉNATION DES TISSUS
Abstract: front page image
(EN)Provided are substituted benzaldehydes and derivatives thereof that act as allosteric modulators of hemoglobin, methods and intermediates for their preparation, pharmaceutical compositions comprising the modulators, and methods for their use in treating disorders mediate by hemoglobin and disorders that would benefit from increased tissue oxygenation.
(FR)La présente invention concerne des benzaldéhydes substitués et des dérivés de ceux-ci qui agissent comme modulateurs allostériques de l'hémoglobine, des procédés et des intermédiaires dans la préparation de ceux-ci, des compositions pharmaceutiques comprenant les modulateurs, et des méthodes d'utilisation de celles-ci dans le traitement de troubles médiés par l'hémoglobine et de troubles qui pourraient bénéficier d'une oxygénation accrue des tissus.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)