Some content of this application is unavailable at the moment.
If this situation persist, please contact us atFeedback&Contact
1. (WO2013084075) METHODS OF DETECTING MUTATIONS AND EPIGENETIC CHANGES
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2013/084075 International Application No.: PCT/IB2012/003094
Publication Date: 13.06.2013 International Filing Date: 06.12.2012
IPC:
C12Q 1/68 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
68
involving nucleic acids
Applicants:
MDXHEALTH SA [BE/BE]; Chu, Tour 5 Giga, Niveau 3 Avenue De I'hopital 11 B-4000 Sart-tilman (liege), BE
Inventors:
VAN CRIEKINGE, Wim; BE
CLARK, James; BE
VANDERSMISSEN, Johan; BE
Priority Data:
61/567,49606.12.2011US
Title (EN) METHODS OF DETECTING MUTATIONS AND EPIGENETIC CHANGES
(FR) MÉTHODES DE DÉTECTION DE MUTATIONS ET DE MODIFICATIONS ÉPIGÉNÉTIQUES
Abstract:
(EN) Disclosed are methods for assessing the rnethylation and mutation status of nucleic acid in a sample. The methods provide for methylation-dependent modification of the nucleic acid in a sample, and subsequently nucleic acid amplification processes to distinguish between mutated and non-mutated target sequence.
(FR) L'invention concerne des méthodes pour évaluer la méthylation et l'état de mutation d'un acide nucléique dans un échantillon. Les méthodes permettent la modification dépendante de la méthylation de l'acide nucléique dans un échantillon, et par conséquent des procédés d'amplification d'acide nucléique pour établir une distinction entre une séquence cible mutée et non mutée.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
CA2858144EP2788505US20140322714