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1. WO2013083606 - KINASE INHIBITORS

Publication Number WO/2013/083606
Publication Date 13.06.2013
International Application No. PCT/EP2012/074450
International Filing Date 05.12.2012
IPC
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
471
Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/-C07D463/251
02
in which the condensed system contains two hetero rings
04
Ortho-condensed systems
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
435
having six-membered rings with one nitrogen as the only ring hetero atom
4353
ortho- or peri-condensed with heterocyclic ring systems
437
the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11
Drugs for disorders of the respiratory system
C07D 471/04 (2006.01)
A61K 31/437 (2006.01)
A61P 11/00 (2006.01)
CPC
A61K 31/437
C07D 471/04
Applicants
  • CHIESI FARMACEUTICI S.P.A. [IT/IT]; Via Palermo, 26/A I-43100 Parma, IT
Inventors
  • VAN NIEL, Monique Bodil; IT
  • RAY, Nicholas Charles; IT
  • ALCARAZ, Lilian; IT
  • PANCHAL, Terry Aaron; IT
  • JENNINGS, Andrew Stephen Robert; IT
  • ARMANI, Elisabetta; IT
  • CRIDLAND, Andrew Peter; IT
  • HURLEY, Christopher; IT
Agents
  • MINOJA, Fabrizio; Bianchetti Bracco Minoja S.R.L. Via Plinio, 63 I-20129 Milano, IT
Priority Data
11192894.109.12.2011EP
12187932.410.10.2012EP
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) KINASE INHIBITORS
(FR) INHIBITEURS DE KINASES
Abstract
(EN)
Compounds of formula (I) or a pharmaceutically acceptable salt thereof: wherein R2, W, A, Y and R1 are as defined in the specification, are p38 MAPK inhibitors, useful as anti-inflammatory agents in the treatment of, inter alia, diseases of the respiratory tract.
(FR)
Composés de formule (I) ou sel pharmaceutiquement acceptable de ceux-ci : formule (I) - R2, W, A, Y et R1 étant tels que définis dans la description, qui sont des inhibiteurs de la MAPK p38, utiles à titre d'agents anti-inflammatoires dans le traitement, inter alia, des maladies des voies respiratoires.
Latest bibliographic data on file with the International Bureau