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Machine translation
1. (WO2013059690) SOLID PHASE FOR MIXED-MODE CHROMATOGRAPHIC PURIFICATION OF PROTEINS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2013/059690    International Application No.:    PCT/US2012/061154
Publication Date: 25.04.2013 International Filing Date: 19.10.2012
IPC:
C07K 1/16 (2006.01), C07K 1/22 (2006.01), C07K 1/36 (2006.01), B01D 15/10 (2006.01), B01D 15/20 (2006.01)
Applicants: BIO-RAD LABORATORIES, INC. [US/US]; 1000 Alfred Nobel Drive Hercules, CA 94547 (US)
Inventors: LIAO, Jiali; (US).
OLECH, Lee; (US).
CHEN, Hong; (US).
HE, Xuemei; (US).
FROST, Russell; (US)
Agent: HEINES, M., Henry; Kilpatrick Townsend & Stockton LLP Two Embarcadero Center, Eighth Floor San Francisco, CA 94111-3834 (US)
Priority Data:
61/549,146 19.10.2011 US
Title (EN) SOLID PHASE FOR MIXED-MODE CHROMATOGRAPHIC PURIFICATION OF PROTEINS
(FR) PHASE SOLIDE POUR UNE PURIFICATION CHROMATOGRAPHIQUE EN MODE MIXTE DE PROTÉINES
Abstract: front page image
(EN)Proteins are purified by a mixed-mode chromatography system formed by attaching a ligand with cation exchange and hydrophobic functionalities to a large-pore support matrix, the only linkage between the ligand and the support matrix being a chain having a backbone of no more than three atoms between the hydrophobic group and the support matrix.
(FR)Selon l'invention, des protéines sont purifiées par un système chromatographique en mode mixte formées par la fixation d'un ligand ayant des fonctionnalités échangeuse de cations et hydrophobe à une matrice de support à larges pores, la seule liaison entre le ligand et la matrice de support étant une chaîne présentant un squelette de pas plus de trois atomes entre le groupe hydrophobe et la matrice de support.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)