WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2013059222) 2-PYRIDYLOXY-4-NITRILE OREXIN RECEPTOR ANTAGONISTS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2013/059222    International Application No.:    PCT/US2012/060479
Publication Date: 25.04.2013 International Filing Date: 17.10.2012
IPC:
C07D 401/14 (2006.01), C07D 409/14 (2006.01), C07D 413/14 (2006.01), C07D 417/14 (2006.01), A61K 31/4545 (2006.01), A61P 25/00 (2006.01), A61P 25/20 (2006.01)
Applicants: MERCK SHARP & DOHME CORP. [US/US]; 126 East Lincoln Avenue Rahway, New Jersey 07065-0907 (US) (For All Designated States Except US).
KUDUK, Scott, D. [US/US]; (US) (NZ, US only).
SKUDLAREK, Jason, W. [US/US]; (US) (NZ, US only)
Inventors: KUDUK, Scott, D.; (US).
SKUDLAREK, Jason, W.; (US)
Common
Representative:
MERCK SHARP & DOHME CORP.; 126 East Lincoln Avenue Rahway, New Jersey 07065-0907 (US)
Priority Data:
61/548,883 19.10.2011 US
Title (EN) 2-PYRIDYLOXY-4-NITRILE OREXIN RECEPTOR ANTAGONISTS
(FR) ANTAGONISTES DES RÉCEPTEURS DE L'OREXINE À BASE DE 2-PYRYDYLOXY-4-NITRILE
Abstract: front page image
(EN)The present invention is directed to 2-pyridyloxy-4-nitrile compounds which are antagonists of orexin receptors. The present invention is also directed to uses of the 2-pyridyl-oxy-4-nitrile compounds described herein in the treatment or prevention of neurological and psychiatric disorders and diseases in which orextn receptors are involved. The present invention is also directed to pharmaceutical compositions comprising these compounds. The present invention is also directed to uses of these pharmaceutical compositions in the prevention or treatment of such diseases in which orexin receptors are involved.
(FR)La présente invention concerne des composés de 2-pyridyloxy-4-nitrile qui sont des antagonistes des récepteurs de l'orexine. La présente invention concerne également des utilisations desdits composés de 2-pyridyloxy-4- nitrile décrits dans ce document dans le traitement ou la prévention de troubles et de maladies neurologiques et psychiatriques, dans lesquels les récepteurs de l'orexine sont impliqués ; des compositions pharmaceutiques renfermant ces composés ; des utilisations desdites compositions pharmaceutiques dans la prévention ou le traitement de ces maladies dans lesquelles les récepteurs de l'orexine sont impliqués.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)