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1. (WO2013057251) HETEROARYL HYDROXAMIC ACID DERIVATIVES AND THEIR USE IN THE TREATMENT, AMELIORATION OR PREVENTION OF A VIRAL DISEASE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2013/057251    International Application No.:    PCT/EP2012/070757
Publication Date: 25.04.2013 International Filing Date: 19.10.2012
Chapter 2 Demand Filed:    21.08.2013    
IPC:
C07D 213/81 (2006.01), C07D 217/26 (2006.01), C07D 401/04 (2006.01), C07D 401/12 (2006.01), C07D 401/14 (2006.01), C07D 405/08 (2006.01), C07D 413/04 (2006.01), C07D 471/04 (2006.01), C07D 495/04 (2006.01), A61K 31/44 (2006.01), A61P 31/16 (2006.01)
Applicants: F. HOFFMANN-LA ROCHE AG [CH/CH]; Grenzacherstrasse 124 CH-4070 Basel (CH).
SAVIRA PHARMACEUTICALS GMBH [AT/AT]; Veterinärplatz 1 Building IA A-1210 Vienna (AT).
EUROPEAN MOLECULAR BIOLOGY LABORATORY [DE/DE]; Meyerhofstraße 1 69117 Heidelberg (DE)
Inventors: CLASSEN-HOUBEN, Dirk; (AT).
WOLKERSTORFER, Andrea; (AT).
SZOLAR, Oliver; (AT).
SMITH, Mark; (US).
SO, Sung-Sau; (US).
CUSACK, Stephen; (FR).
LANGER, Thierry; (FR).
GIETHLEN, Bruno; (FR).
MORICE, Christophe; (FR).
MICHAUT-SIMON, Céline; (FR).
ZUBIETA, Chloe; (FR)
Agent: VOSSIUS & PARTNER; Siebertstraße 4 81675 München (DE)
Priority Data:
61/550,045 21.10.2011 US
Title (EN) HETEROARYL HYDROXAMIC ACID DERIVATIVES AND THEIR USE IN THE TREATMENT, AMELIORATION OR PREVENTION OF A VIRAL DISEASE
(FR) DÉRIVÉS D'ACIDE HÉTÉROARYL-HYDROXAMIQUE ET LEUR UTILISATION POUR TRAITER, AMÉLIORER OU PRÉVENIR UNE MALADIE VIRALE
Abstract: front page image
(EN)The present invention relates to a compound having the general formula I, optionally in the form of a pharmaceutically acceptable salt, solvate, polymorph, prodrug, tautomer, racemate, enantiomer, or dsasiereomer or mixture thereof, which is useful in treating, ameloriating or preventing a viral disease. Furthermore, specific combination therapies are disclosed.
(FR)La présente invention concerne un composé représenté par la formule générale (I), éventuellement sous la forme d'un sel, solvate, polymorphe, promédicament, tautomère, racémate, énantiomère ou diastéréomère pharmaceutiquement acceptable, ou d'un mélange de ceux-ci, ce composé étant utile pour traiter, améliorer ou prévenir une maladie virale. L'invention concerne en outre des polythérapies spécifiques.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)