CN2012078069 METHOD FOR RAPIDLY MEASURING MELATONIN ADULTERATION OF CHINESE PATENT MEDICINE OR HEALTHCARE FOOD

1. (WO2013056572) METHOD FOR RAPIDLY MEASURING MELATONIN ADULTERATION OF CHINESE PATENT MEDICINE OR HEALTHCARE FOOD

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Latest bibliographic data on file with the International Bureau

Pub. No.:		WO/2013/056572		International Application No.:		PCT/CN2012/078069
Publication Date:		25.04.2013		International Filing Date:		02.07.2012

IPC:

G01N 21/78 (2006.01), G01N 1/28 (2006.01)

Applicants:

SHENZHEN INSTITUTE FOR DRUG CONTROL [CN/CN]; No.28 2nd Middle Hi-tech Street, Nanshan District Shenzhen, Guangdong 518057 (CN) (For All Designated States Except US).
WANG, Tiejie [CN/CN]; (CN) (For US Only).
LU, Yi [CN/CN]; (CN) (For US Only).
XIAO, Lihe [CN/CN]; (CN) (For US Only).
GUAN, Xiaoying [CN/CN]; (CN) (For US Only).
HAN, Dongqi [CN/CN]; (CN) (For US Only).
YIN, Guo [CN/CN]; (CN) (For US Only).
WANG, Jue [CN/CN]; (CN) (For US Only).
LI, Xueqing [CN/CN]; (CN) (For US Only).
YAN, Yan [CN/CN]; (CN) (For US Only)

Inventors:

WANG, Tiejie; (CN).
LU, Yi; (CN).
XIAO, Lihe; (CN).
GUAN, Xiaoying; (CN).
HAN, Dongqi; (CN).
YIN, Guo; (CN).
WANG, Jue; (CN).
LI, Xueqing; (CN).
YAN, Yan; (CN)

Agent:

GUANGZHOU SCIHEAD PATENT AGENT CO.. LTD; Room 1508, Huihua Commercial & Trade Building No.80, Xianlie Zhong Road, Yuexiu Guangzhou, Guangdong 510070 (CN)

Priority Data:

201110316788.3

18.10.2011

Title

(EN) METHOD FOR RAPIDLY MEASURING MELATONIN ADULTERATION OF CHINESE PATENT MEDICINE OR HEALTHCARE FOOD
(FR) PROCÉDÉ DE DÉTERMINATION RAPIDE DU DOPAGE PAR MÉLATONINE CONTENUE DANS LES ALIMENTS SAINS ET DANS LES MÉDICAMENTS CHINOIS BREVETÉS
(ZH) 中成药和保健食品中掺杂褪黑素的快速测定方法

Abstract:

(EN)A method for rapidly measuring melatonin adulteration of Chinese patent medicines and healthcare foods comprises: (1) extracting melatonin added to a Chinese patent medicine or healthcare food by using ethyl acetate; and (2) adding (Dimethylamino)cinnamic acid to the extracted solution, and observing color. The method is rapid, simple and convenient, has strong specificity, high accuracy, reaction sensitivity, and a wide application range, and is applicable to on-site detection of melatonin adulteration of a Chinese patent medicine or healthcare food.
(FR)Procédé de détermination rapide du dopage par mélatonine contenue dans les aliments sains et dans les médicaments chinois brevetés consistant à : extraire avec de l'acétate d'éthyle la mélatonine contenue dans les aliments sains ou les médicaments chinois brevetés; et à ajouter à l'extrait un acide cinnamique diméthylamino pour observer la couleur. Ce procédé est rapide, simple, pratique, à fortes spécificité et précision tout en étant sensible, ce qui lui confère un large spectre d'applications, notamment pour déterminer s'il y a ou non ajout de mélatonine dans les aliments sains et les médicaments chinois brevetés.
(ZH)一种中成药和保健食品中掺杂褪黑素的快速测定方法，包括（1）用乙酸乙酯提取中成药或保健食品中的褪黑素；（2）向提取液中加入对二甲基氨基肉桂酸，观察颜色。该方法快速、简便，专属性强、准确率高，反应灵敏，适用范围广，适用于现场检验中成药和保健食品中是否掺入了褪黑素。

Designated States:

AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).

Publication Language:	Chinese (ZH)
Filing Language:	Chinese (ZH)

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