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1. (WO2013056453) PREPARATION METHOD AND APPLICATION OF INJECTION FOR NEEDLELESS INJECTION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2013/056453    International Application No.:    PCT/CN2011/081064
Publication Date: 25.04.2013 International Filing Date: 20.10.2011
IPC:
A61K 9/14 (2006.01), A61K 9/18 (2006.01), A61K 9/19 (2006.01), A61K 38/00 (2006.01), A61K 38/21 (2006.01), A61K 38/28 (2006.01), A61K 39/00 (2006.01), A61K 39/39 (2006.01), A61K 47/02 (2006.01), A61P 3/10 (2006.01), A61P 31/04 (2006.01), A61P 31/14 (2006.01), A61P 31/20 (2006.01), A61P 35/00 (2006.01), A61P 7/00 (2006.01), A61P 17/00 (2006.01)
Applicants: 302 MILITARY HOSPITAL OF CHINA [CN/CN]; 100#, West Fourth Ring Road, Fengtai District Beijing 100039 (CN) (For All Designated States Except US).
WANG, Jiabo [CN/CN]; (CN) (For US Only).
XIAO, Xiaohe [CN/CN]; (CN) (For US Only).
LI, Qi [CN/CN]; (CN) (For US Only)
Inventors: WANG, Jiabo; (CN).
XIAO, Xiaohe; (CN).
LI, Qi; (CN)
Agent: AFD CHINA INTELLECTUAL PROPERTY LAW OFFICE; Suite B 1601A, 8 Xue Qing Rd., Haidian Beijing 100192 (CN)
Priority Data:
Title (EN) PREPARATION METHOD AND APPLICATION OF INJECTION FOR NEEDLELESS INJECTION
(FR) PROCÉDÉ DE PRÉPARATION D'UNE SERINGUE D'INJECTION SANS AIGUILLE SOUS FORME DE POUDRE ET SES APPLICATIONS
(ZH) 一种无针注射用注射剂的制备方法及应用
Abstract: front page image
(EN)An injection for needleless injection, in the form of powder, comprises a biological product and an inorganic salt with water of crystallization removed, a mass ratio of the biological product to the inorganic salt being 1:20 to 1:80. The powder is solid particles formed of the biological product wrapped by an external surface of the inorganic salt with water of crystallization removed. The particle diameter of the powder is 20 to 200 micrometers, and preferably, 50 to 70 micrometers. The injection of the present invention may also comprise a tackifier or a Chinese medicinal adjuvant. The mass ratio of the biological product to the tackifier or Chinese medicinal adjuvant to the inorganic salt with water of crystallization removed is 1:0.2:20 to 1:10:80. Also disclosed are a preparation method of the injection for needleless injection, applications of the injection in preparing medicine for preventing or curing diseases, and a method for performing needleless injection by using the injection.
(FR)Seringue d'injection sans aiguille sous forme de poudre et comprenant en rapport de masse de 1:20 à 1:80 de produits biologiques et de sels inorganiques exempts d'eau de cristallisation, la poudre se présente sous forme de particules solides enrobant les sels inorganiques exempts d'eau de cristallisation et les produits biologiques. La granulométrie de la poudre est de 20 à 200 microns, de préférence de 50 à 70 microns. La seringue de cette invention comprend aussi une résine tackifiante ou un adjuvant de médecine traditionnelle chinoise (MTC) où les produits biologiques sont: une résine tackifiante ou un adjuvant de MTC, le rapport de masse des sels inorganiques exempts d'eau de cristallisation étant de 1:0,2:20-1:10:80. On prévoit en outre un procédé de préparation d'une seringue d'injection sans aiguille dont les applications sont la préparation de médicaments pour la prévention ou le traitement de maladies lors d'une injection sans aiguille.
(ZH)一种无针注射用注射剂,该注射剂呈粉末形式,包含质量比为1:20-1:80的生物制品和脱结晶水无机盐,所述粉末为所述生物制品包裹在所述脱结晶水无机盐外表面的实心颗粒。所述粉末粒径为20-200微米,优选为50-70微米。本发明的注射剂还可以包含增粘剂或中药佐剂,其中,生物制品:增粘剂或中药佐剂:脱结晶水无机盐的质量比为1:0.2:20-1:10:80。本发明还公开了所述无针注射用注射剂的制备方法,其用于制备预防或治疗疾病的药物的用途,以及使用其进行无针注射的方法。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)