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Machine translation
1. (WO2013056352) ANTIBODIES AND ANTIBODY FRAGMENTS TARGETING SIRP-ALPHA AND THEIR USE IN TREATING HEMATOLOGIC CANCERS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2013/056352    International Application No.:    PCT/CA2012/000964
Publication Date: 25.04.2013 International Filing Date: 19.10.2012
IPC:
C07K 16/28 (2006.01), A61K 39/395 (2006.01), A61P 35/00 (2006.01), A61P 35/02 (2006.01), C07K 16/18 (2006.01), C12N 15/13 (2006.01)
Applicants: UNIVERSITY HEALTH NETWORK [CA/CA]; 190 Elizabeth Street R. Fraser Elliott Building - Room 1S-417 Toronto, Ontario M5G 2C4 (CA) (For All Designated States Except US).
THE HOSPITAL FOR SICK CHILDREN [CA/CA]; 555 University Avenue Toronto, Ontario M5G 1X8 (CA) (For All Designated States Except US).
WANG, Jean C. Y. [CA/CA]; (CA) (US only).
DANSKA, Jayne S. [US/CA]; (CA) (US only).
DICK, John [CA/CA]; (CA) (US only).
SIDHU, Sachdev [CA/CA]; (CA) (US only).
UPPALAPATI, Maruti [IN/CA]; (CA) (US only)
Inventors: WANG, Jean C. Y.; (CA).
DANSKA, Jayne S.; (CA).
DICK, John; (CA).
SIDHU, Sachdev; (CA).
UPPALAPATI, Maruti; (CA)
Agent: NORTON ROSE FULBRIGHT CANADA LLP/S.E.N.C.R.L., S.R.L.; 1 Place Ville Marie Suite 2500 Montreal, Québec H3B 1R1 (CA)
Priority Data:
61/548,817 19.10.2011 US
Title (EN) ANTIBODIES AND ANTIBODY FRAGMENTS TARGETING SIRP-ALPHA AND THEIR USE IN TREATING HEMATOLOGIC CANCERS
(FR) ANTICORPS ET FRAGMENTS D'ANTICORPS CIBLANT SIRP-ALPHA ET LEUR UTILISATION POUR LE TRAITEMENT DE CANCERS HÉMATOLOGIQUES
Abstract: front page image
(EN)The invention relates to modulating the SIRPα - CD47 interaction in order to treat hematological cancer and compounds therefor. In particular, there is also provided SIRPα antibodies and antibody fragments, preferably used for treating hematological cancer.
(FR)L'invention concerne la modulation de l'interaction SIRPα - CD47 afin de traiter un cancer hématologique et des composés associés. L'invention concerne également notamment des anticorps SIRPα et des fragments d'anticorps, de préférence utilisés pour le traitement d'un cancer hématologique.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)