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1. (WO2013056222) CAUSATIVE AGENTS AND DIAGNOSTIC METHODS RELATING TO RHEUMATOID ARTHRITIS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2013/056222    International Application No.:    PCT/US2012/060234
Publication Date: 18.04.2013 International Filing Date: 15.10.2012
IPC:
C12Q 1/04 (2006.01), C12Q 1/68 (2006.01)
Applicants: NEW YORK UNIVERSITY [US/US]; One Park Avenue - 6th Floor New York, NY 10016-5802 (US) (For All Designated States Except US).
MEMORIAL SLOAN-KETTERING CANCER CENTER [US/US]; 1275 York Avenue New York, NY 10021 (US) (For All Designated States Except US).
ABRAMSON, Steven, B. [US/US]; (US) (US only).
SCHER, Jose, U. [AR/US]; (US) (US only).
LITTMAN, Dan, R. [US/US]; (US) (US only).
PAMER, Eric, G. [US/US]; (US) (US only)
Inventors: ABRAMSON, Steven, B.; (US).
SCHER, Jose, U.; (US).
LITTMAN, Dan, R.; (US).
PAMER, Eric, G.; (US)
Agent: FASHENA, Sarah, J.; Klauber & Jackson, LLC 25 East Spring Valley Avenue-suite 160 Maywood, NJ 07607 (US)
Priority Data:
61/627,627 14.10.2011 US
Title (EN) CAUSATIVE AGENTS AND DIAGNOSTIC METHODS RELATING TO RHEUMATOID ARTHRITIS
(FR) AGENTS ÉTIOLOGIQUES ET MÉTHODES DE DIAGNOSTIC ASSOCIÉES À LA POLYARTHRITE RHUMATOÏDE
Abstract: front page image
(EN)Methods, reagents and compositions thereof for predicting RA onset in susceptible individuals, diagnosing RA onset, and/or evaluating efficacy of a therapeutic regimen for treating RA are described herein. Determining the amount of a particular bacterial species comprising SEQ ID NO: 1, SEQ ID NO: 2, or SEQ ID NO: 3 (SEQ ID NO: 1+ bacteria) serves as a biomarker for the above indications.
(FR)La présente invention concerne des procédés, des réactifs et des compositions de ceux-ci qui permettent de prédire l'apparition de la polyarthrite rhumatoïde (RA) chez des individus susceptibles, le diagnostic de l'apparition de RA et/ou l'évaluation de l'efficacité d'un traitement pour traiter RA. La détermination de la quantité d'espèces bactériennes particulières comportant SEQ ID NO:1, SEQ ID NO:2, ou SEQ ID NO:3 (SEQ ID NO:1 + bactéries) sert en tant que biomarqueur pour les indications susmentionnées.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)