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Machine translation
1. (WO2013056159) METHODS AND COMPOSITIONS FOR RAPID TRANSBUCCAL DELIVERY OF ACTIVE AGENTS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2013/056159    International Application No.:    PCT/US2012/060107
Publication Date: 18.04.2013 International Filing Date: 12.10.2012
IPC:
A61K 9/00 (2006.01), A61K 31/465 (2006.01)
Applicants: JALEVA PHARMACEUTICALS, LLC [US/US]; Bunker Hill Street Suite 117C 3030 San Diego, California 92109 (US)
Inventors: BATTAGLIA, Alex; (US)
Agent: BRINCKERHOFF, Courtenay C.; Foley & Lardner LLP 3000 K Street NW Suite 600 Washington, District of Columbia 20007-5109 (US)
Priority Data:
61/546,702 13.10.2011 US
Title (EN) METHODS AND COMPOSITIONS FOR RAPID TRANSBUCCAL DELIVERY OF ACTIVE AGENTS
(FR) PROCÉDÉS ET COMPOSITIONS POUR ADMINISTRATION RAPIDE D'AGENTS ACTIFS PAR LA BOUCHE
Abstract: front page image
(EN)A method of rapid transbuccal delivery of an active agent into the bloodstream is provided. The method can include providing a pharmaceutical composition comprising the active agent, resin and a volatile solvent and, optionally, water. In some embodiments, the method achieves a Tmax 60 minutes or less, an onset of therapeutic effect of 60 minutes or less, and/or achieves therapeutic serum levels of the active agent within 60 minutes or less. Related compositions also are provided.
(FR)L'invention concerne un procédé d'administration rapide, dans la circulation sanguine, d'un agent actif par la bouche. Le procédé peut consister à fournir une composition pharmaceutique comportant l'agent actif, de la résine et un solvant volatil et, facultativement, de l'eau. Dans certains modes de réalisation, le procédé atteint un temps maximal de 60 minutes ou moins, une apparition de l'effet thérapeutique de 60 minutes ou moins, et/ou atteint des niveaux de sérum thérapeutique de l'agent actif en 60 minutes ou moins. L'invention concerne également des compositions associées.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)