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Machine translation
1. (WO2013054320) ANTIBODIES TO CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE (CEACAM)
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2013/054320    International Application No.:    PCT/IL2011/000808
Publication Date: 18.04.2013 International Filing Date: 11.10.2011
IPC:
A61K 39/395 (2006.01)
Applicants: TEL HASHOMER MEDICAL RESEARCH INFRASTRUCTURE AND SERVICES LTD. [IL/IL]; The Chaim Sheba Medical Center Tel Hashomer 52621 Ramat Gan (IL) (For All Designated States Except US).
RAMOT AT TEL-AVIV UNIVERSITY LTD. [IL/IL]; P.O. Box 39296 6139201 Tel Aviv (IL) (For All Designated States Except US).
MARKEL, Gal [IL/IL]; (IL) (For US Only).
CCAM BIOTHERAPEUTICS LTD. [--/IL]; Tel- Hai Industrial Park P.O. Box 408 11013 Kiryat-Shmona (IL) (For All Designated States Except US).
BEN MOSHE, Tehila [IL/IL]; (IL) (For US Only).
SAPIR, Yair [IL/IL]; (IL) (For US Only).
MANDEL, Ilana [IL/IL]; (IL) (For US Only).
SCHACHTER, Jacob [IL/IL]; (IL) (For US Only).
ORTENBERG, Rona [IL/IL]; (IL) (For US Only)
Inventors: MARKEL, Gal; (IL).
BEN MOSHE, Tehila; (IL).
SAPIR, Yair; (IL).
MANDEL, Ilana; (IL).
SCHACHTER, Jacob; (IL).
ORTENBERG, Rona; (IL)
Agent: WEBB, Cynthia; Webb & Co. P.O. Box 2189 76121 Rehovot (IL)
Priority Data:
Title (EN) ANTIBODIES TO CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE (CEACAM)
(FR) ANTICORPS DIRIGÉS CONTRE LA MOLÉCULE D'ADHÉSION CELLULAIRE ASSOCIÉE À L'ANTIGÈNE CARCINO-EMBRYONNAIRE (CEACAM)
Abstract: front page image
(EN)The present invention provides antibodies, as well as molecules having at least the antigen-binding portion of an antibody, recognizing the protein CEACAM1 and other subtypes of the CEACAM protein family. Disclosed antibodies and antibody fragments are characterized by comprising specific CDR sequences. Methods of production and use in therapy and diagnosis, of such antibodies and antibody fragments are also provided.
(FR)La présente invention concerne des anticorps, ainsi que des molécules ayant au moins la partie de liaison à l'antigène d'un anticorps, reconnaissant la protéine CEACAM1 et d'autres sous-types de la famille des protéines CEACAM. Des anticorps et des fragments d'anticorps de l'invention sont caractérisés en ce qu'ils comprennent des séquences CDR spécifiques. L'invention concerne également des procédés de production et d'utilisation en thérapie et pour l'établissement de diagnostics desdits anticorps et fragments d'anticorps.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)