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1. (WO2013053080) ANTI-TUMOUR FUSION PROTEIN AND CODING GENE AND USE THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2013/053080    International Application No.:    PCT/CN2011/001711
Publication Date: 18.04.2013 International Filing Date: 12.10.2011
IPC:
C07K 19/00 (2006.01), C12N 15/62 (2006.01), C12N 15/63 (2006.01), A61K 38/16 (2006.01), A61P 35/00 (2006.01)
Applicants: INSTITUTE OF BIOTECHNOLOGY, CHINESE ACADEMY OF MILITARY MEDICAL SCIENCES [CN/CN]; 20 Dongdajie Street, Fengtai District Beijing 100071 (CN) (For All Designated States Except US).
LIU, Zhimin [CN/CN]; (CN) (For US Only).
ZHAO, Hongliang [CN/CN]; (CN) (For US Only).
XUE, Chong [CN/CN]; (CN) (For US Only).
DU, Jiliang [CN/CN]; (CN) (For US Only).
REN, Min [CN/CN]; (CN) (For US Only).
XIA, Shan [CN/CN]; (CN) (For US Only)
Inventors: LIU, Zhimin; (CN).
ZHAO, Hongliang; (CN).
XUE, Chong; (CN).
DU, Jiliang; (CN).
REN, Min; (CN).
XIA, Shan; (CN)
Agent: JEEKAI & PARTNERS; Suite 602, Jinyu Tower A129 West Xuan Wu Men Street Xicheng District Beijing 100031 (CN)
Priority Data:
Title (EN) ANTI-TUMOUR FUSION PROTEIN AND CODING GENE AND USE THEREOF
(FR) PROTÉINE DE FUSION ANTITUMORALE, ET GÈNE CODANT ET UTILISATION ASSOCIÉS
(ZH) 一种抗肿瘤融合蛋白及其编码基因和应用
Abstract: front page image
(EN)Provided in the present invention is an anti-tumour fusion protein, wherein the fusion protein has an Onc protein consisting of 20-123 amino acid residues of SEQ ID ΝΟ:1, an HSA protein consisting of 144-728 amino acid residues of SEQ ID ΝΟ:1, and a 4D5MOCB polypeptide fragment consisting of 739-990 amino acid residues of SEQ ID ΝΟ:1. The present invention also provides the coding gene and the use of the fusion protein.
(FR)La présente invention concerne une protéine de fusion antitumorale, la protéine de fusion comprenant une protéine Onc constituée de 20 à 123 résidus d'acides aminés de SEQ ID ΝΟ : 1, une protéine HSA constituée de 144 à 728 résidus d'acides aminés de SEQ ID ΝΟ : 1 et un fragment de polypeptide 4D5MOCB constitué de 739 à 990 résidus d'acides amines de SEQ ID ΝΟ : 1. La présente invention concerne également le gène codant et l'utilisation de la protéine de fusion.
(ZH)本发明提供了一种抗肿瘤融合蛋白,所述融合蛋白具有Onc蛋白、HSA蛋白和4D5MOCB多肽片段,Onc蛋白由SEQ ID ΝΟ:1第20-123位氨基酸残基组成,HSA蛋白由SEQ ID ΝΟ:1第144-728位氨基酸残基组成,4D5MOCB多肽片段由SEQ ID NO:1第739-990位氨基酸残基组成。本发明还提供了所述融合蛋白的编码基因及其应用。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)