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Machine translation
1. (WO2013053065) METHODS AND KITS FOR DIAGNOSING AND/OR PROGNOSING OSTEOARTHRITIS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2013/053065    International Application No.:    PCT/CA2012/050723
Publication Date: 18.04.2013 International Filing Date: 15.10.2012
IPC:
G01N 33/48 (2006.01), G01N 33/53 (2006.01), G01N 33/68 (2006.01)
Applicants: HÔPITAL STE-JUSTINE [CA/CA]; Local A-935 3175, Côte Ste-Catherine Montréal, Québec H3T 1C5 (CA)
Inventors: MOREAU, Alain; (CA)
Agent: GOUDREAU GAGE DUBUC; 2000, McGill College #2200 Montréal, Québec H3A 3H3 (CA)
Priority Data:
61/547,275 14.10.2011 US
Title (EN) METHODS AND KITS FOR DIAGNOSING AND/OR PROGNOSING OSTEOARTHRITIS
(FR) PROCÉDÉS ET KITS POUR LE DIAGNOSTIC ET/OU LE PRONOSTIC DE L'OSTÉOARTHRITE
Abstract: front page image
(EN)A method of determining whether a subject is at risk of developing osteoarthritis (OA), said method comprising: determining the cellular localization of a Prohibitin-1 (PHB1) polypeptide and/or Small Ubiquitin-like Modifier (SUMO) polypeptide and/or UBC9, in a cell sample from said subject; and determining whether said subject is at risk of developing OA based on the cellular localization of a PHB1 polypeptide and/or SUMO and/or UBC9 polypeptide, is described.
(FR)L'invention concerne un procédé de détermination du risque d'un sujet de développer une ostéoarthrite (OA), ledit procédé comprenant : la détermination de l'emplacement cellulaire d'un polypeptide prohibitine-1 (PHB1) et/ou d'un polypeptide SUMO (Small Ubiquitin-like Modifier) et/ou UBC9 dans un échantillon cellulaire dudit sujet ; et la détermination du risque dudit sujet de développer une OA à partir de l'emplacement cellulaire d'un polypeptide PHB1 et/ou d'un polypeptide SUMO et/ou UBC9.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)