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1. (WO2013052550) NOVEL IMIDAZOLE QUINOLINE-BASED IMMUNE SYSTEM MODULATORS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2013/052550    International Application No.:    PCT/US2012/058566
Publication Date: 11.04.2013 International Filing Date: 03.10.2012
IPC:
A61K 31/535 (2006.01), C07D 471/00 (2006.01), A01N 43/42 (2006.01), A61K 31/44 (2006.01)
Applicants: JANUS BIOTHERAPEUTICS, INC. [US/US]; 222 Third Street Suite 2240 Cambridge, MA 02142 (US).
LIPFORD, Grayson, B. [US/US]; (US).
ZEPP, Charles, M. [US/US]; (US)
Inventors: LIPFORD, Grayson, B.; (US).
ZEPP, Charles, M.; (US)
Agent: GU, Henry; Wilmer Cutler Pickering Hale And Dorr LLP 60 State Street Boston, MA 02109 (US)
Priority Data:
61/543,082 04.10.2011 US
Title (EN) NOVEL IMIDAZOLE QUINOLINE-BASED IMMUNE SYSTEM MODULATORS
(FR) NOUVEAUX MODULATEURS DU SYSTÈME IMMUNITAIRE À BASE D'IMIDAZOLE QUINOLINE
Abstract: front page image
(EN)The present invention relates to a compound of Formula (I): or an enantiomer, diastereomer, tautomer, or pharmaceutically acceptable salt or solvate thereof, wherein the symbols are as defined in the specification; a pharmaceutical composition comprising the same; and a method for treating or preventing autoimmunity disease using the same.
(FR)La présente invention concerne un composé de formule I : ou un énantiomère, un diastéréomère, un tautomère de ce dernier, ou un sel ou un solvate pharmaceutiquement acceptable de ce dernier, dont les symboles sont définis dans la description. L'invention porte également sur une composition pharmaceutique le comprenant, et sur une méthode de traitement ou de prévention d'une maladie auto-immunitaire au moyen de ce dernier.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)