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1. (WO2013051767) NOVEL USE OF ANGIOGENIN
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2013/051767    International Application No.:    PCT/KR2012/001466
Publication Date: 11.04.2013 International Filing Date: 27.02.2012
IPC:
A61K 38/17 (2006.01), C07K 14/15 (2006.01), A61P 29/00 (2006.01), A61P 35/00 (2006.01)
Applicants: CHUNG-ANG UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION [KR/KR]; 221 Heukseok-dong, Dongjak-gu Seoul 156-861 (KR) (For All Designated States Except US).
KIM, Jae-Chan [KR/KR]; (KR) (For US Only).
OH, Doo-Hwan [KR/KR]; (KR) (For US Only).
JOO, Kwang-Sic [KR/KR]; (KR) (For US Only).
CHUN, Yeoun-Sook [KR/KR]; (KR) (For US Only).
WEE, Sung Wook [KR/KR]; (KR) (For US Only).
KIM, Kyoung Woo [KR/KR]; (KR) (For US Only)
Inventors: KIM, Jae-Chan; (KR).
OH, Doo-Hwan; (KR).
JOO, Kwang-Sic; (KR).
CHUN, Yeoun-Sook; (KR).
WEE, Sung Wook; (KR).
KIM, Kyoung Woo; (KR)
Agent: TAEBAEK INTELLECTUAL PROPERTY LAW FIRM; #601, innoplex 1-cha, 151, Gasan digital 1-ro Geumcheon-gu Seoul 153-803 (KR)
Priority Data:
10-2011-0101899 06.10.2011 KR
10-2011-0102598 07.10.2011 KR
Title (EN) NOVEL USE OF ANGIOGENIN
(FR) UTILISATION INÉDITE DE L'ANGIOGÉNINE
(KO) 안지오제닌의 신규 용도
Abstract: front page image
(EN)The present invention relates to a pharmaceutical composition including angiogenin or a fraction of angiogenin as an effective ingredient for preventing or treating glaucoma. The angiogenin or a fraction thereof may increase the generation of NO, enlarge Schelemm's canal, and increase the intercellular gap to activate aqueous humor outflow and to reduce intraocular pressure. Thus, the angiogenin or a fraction thereof may be effectively used for preventing and treating glaucoma.
(FR)La présente invention concerne une composition pharmaceutique contenant de l'angiogénine ou une fraction d'angiogénine en tant que principe actif pour la prévention ou le traitement du glaucome. Ladite angiogénine ou fraction d'angiogénine se révèle capable de stimuler la génération de NO et d'élargir le canal de Schlemm et l'espace intercellulaire afin d'activer l'évacuation de l'humeur aqueuse et de réduire la pression intraoculaire. Ainsi, ladite angiogénine ou fraction d'angiogénine peut être efficacement utilisée à des fins de prévention et de traitement du glaucome.
(KO)본 발명은 안지오제닌 또는 그의 단편을 유효성분으로 포함하는 녹내장의 예방 또는 치료용 약학 조성물을 제공한다. 본 발명의 안지오제닌 또는 그의 단편은 NO 생성 증가 및 쉴렘관의 확장과 세포간 간격 증가를 통한 방수유출 활성화를 통해 안압을 하강시키는 효과를 보여, 녹내장의 예방 및 치료에 유용하게 사용될 수 있다.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Korean (KO)
Filing Language: Korean (KO)