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Machine translation
1. (WO2013050617) STRUCTURED POLYPEPTIDES WITH SARCOSINE LINKERS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2013/050617    International Application No.:    PCT/EP2012/069899
Publication Date: 11.04.2013 International Filing Date: 08.10.2012
IPC:
A61K 47/48 (2006.01)
Applicants: BICYCLE THERAPEUTICS LIMITED [GB/GB]; Meditrina Building Babraham Research Campus Cambridge Cambridgeshire CB22 3AT (GB) (For All Designated States Except US).
TITE, John [GB/GB]; (GB) (US only).
TEUFEL, Daniel [GB/GB]; (GB) (US only)
Inventors: TITE, John; (GB).
TEUFEL, Daniel; (GB)
Agent: MASCHIO, Antonio; 20 Carlton Crescent Southampton SO15 2ET (GB)
Priority Data:
1117428.1 07.10.2011 GB
Title (EN) STRUCTURED POLYPEPTIDES WITH SARCOSINE LINKERS
(FR) POLYPEPTIDES STRUCTURÉS RENFERMANT DES LIEURS SARCOSINES
Abstract: front page image
(EN)The invention provides a polypeptide ligand comprising a polypeptide comprising at least three reactive groups, separated by at least two loop sequences, and a molecular scaffold which forms covalent bonds with the reactive groups of the polypeptide such that at least two polypeptide loops are formed on the molecular scaffold, further comprising an amino acid polymer comprising at least two sarcosine monomers.
(FR)L'invention porte sur un ligand polypeptidique comprenant un polypeptide comprenant au moins trois groupes réactifs, séparés par au moins deux séquences en boucle, et un échafaudage moléculaire qui forme des liaisons covalentes avec les groupes réactifs du polypeptide de façon à ce qu'au moins deux boucles polypeptidiques soient formées sur l'échafaudage moléculaire, comprenant en outre un polymère d'acides aminés comprenant au moins deux monomères sarcosines.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)