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Machine translation
1. (WO2013049859) TREATING PANCREATIC CANCER AND NON-SMALL CELL LUNG CANCER WITH ATR INHIBITORS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2013/049859    International Application No.:    PCT/US2012/058374
Publication Date: 04.04.2013 International Filing Date: 01.10.2012
IPC:
A61K 31/505 (2006.01), A61K 31/506 (2006.01), A61P 35/00 (2006.01)
Applicants: VERTEX PHARMACEUTICALS INCORPORATED [US/US]; 130 Waverly Street Cambridge, MA 02139 (US) (For All Designated States Except US).
POLLARD, John, Robert [GB/GB]; (GB) (US only).
REAPER, Philip, Michael [GB/GB]; (GB) (US only)
Inventors: POLLARD, John, Robert; (GB).
REAPER, Philip, Michael; (GB)
Agent: CHE, Jennifer G.; Vertex Pharmaceuticals Incorporated 130 Waverly Street Cambridge, MA 02139 (US)
Priority Data:
61/542,084 30.09.2011 US
Title (EN) TREATING PANCREATIC CANCER AND NON-SMALL CELL LUNG CANCER WITH ATR INHIBITORS
(FR) TRAITEMENT DU CANCER DU PANCRÉAS ET DU CANCER DU POUMON NON À PETITES CELLULES AVEC DES INHIBITEURS DE L'ATR
Abstract: front page image
(EN)This invention relates to methods and compositions for treating pancreatic cancer. More specifically, this invention relates to treating pancreatic cancer with certain ATR inhibitors in combination with gemcitabine and/or radiation therapy. This invention also relates to methods and compositions for treating non- small cell lung cancer. More specifically, this invention relates to treating non-small cell lung cancer with an ATR inhibitor in combination with cisplatin or carboplatin, etoposide, and ionizing radiation.
(FR)La présente invention concerne des méthodes et des compositions pour traiter le cancer du pancréas. Plus particulièrement, la présente invention concerne le traitement du cancer du pancréas avec certains inhibiteurs de l'ATR en association avec la gemcitabine et/ou une radiothérapie. La présente invention concerne également des méthodes et des compositions pour traiter le cancer du poumon non à petites cellules. Plus particulièrement, la présente invention concerne le traitement du cancer du poumon non à petites cellules avec un inhibiteur de l'ATR en association avec le cisplatine ou le carboplatine, l'étoposide, et le rayonnement ionisant.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)