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Machine translation
1. (WO2013049719) COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2013/049719    International Application No.:    PCT/US2012/058117
Publication Date: 04.04.2013 International Filing Date: 28.09.2012
IPC:
C07D 265/30 (2006.01), C07D 401/04 (2006.01), C07D 413/04 (2006.01), C07D 413/14 (2006.01), A61K 31/497 (2006.01), A61P 35/00 (2006.01)
Applicants: VERTEX PHARMACEUTICALS INCORPORATED [US/US]; 130 Waverly Street Cambridge, MA 02139 (US) (For All Designated States Except US).
CHARRIER, Jean-Damien [FR/GB]; (GB) (US only).
YOUNG, Stephen, Clinton [FR/GB]; (GB) (US only).
DAVIS, Christopher, John [GB/GB]; (GB) (US only).
STUDLEY, John [BE/GB]; (GB) (US only)
Inventors: CHARRIER, Jean-Damien; (GB).
YOUNG, Stephen, Clinton; (GB).
DAVIS, Christopher, John; (GB).
STUDLEY, John; (GB)
Agent: CHE, Jennifer G.; Vertex Pharmaceuticals Incorporated 130 Waverly Street Cambridge, MA 02139 (US)
Priority Data:
61/620,708 05.04.2012 US
61/541,873 30.09.2011 US
61/554,182 01.11.2011 US
Title (EN) COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE
(FR) COMPOSÉS UTILES EN TANT QU'INHIBITEURS DE KINASE ATR
Abstract: front page image
(EN)The invention relates to the compound 5-(4-isopropylsulfonylphenyl) -3-[3-[4-[(3R)-morpholin-3-yl]phenyl]isoxazol-5-yl]pyrazine-2-amine and pharmaceutically acceptable salts thereof. The compounds are useful as inhibitors of ATR kinase.
(FR)La présente invention concerne le composé 5-(4-isopropylsulfonylphényl)-3-[3-[4-[(3R)-morpholin-3-yl]phényl]isoxazol-5-yl]pyrazine-2-amine et des sels pharmaceutiquement acceptables de celui-ci. Les composés sont utiles en tant qu'inhibiteurs de kinase ATR.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)