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1. (WO2013049567) COMPOUNDS FOR THE TREATMENT OF MYCOBACTERIAL INFECTIONS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2013/049567    International Application No.:    PCT/US2012/057913
Publication Date: 04.04.2013 International Filing Date: 28.09.2012
IPC:
A61K 31/352 (2006.01)
Applicants: THE BROAD INSTITUTE, INC. [US/US]; 7 Cambridge Center Cambridge, MA 02142 (US).
MASSACHUSETTS GENERAL HOSPITAL [US/US]; 55 Fruit Street Boston, MA 02144 (US)
Inventors: HUNG, Deborah; (US).
STANLEY, Sarah; (US).
KAWATE, Tomohiko; (US).
IWASE, Noriakie; (JP).
SHIMIZU, Motohisa; (JP)
Agent: ISSAC, Roy P.; Elmore Patent Law Group 484 Groton Road Westford, MA 01886 (US)
Priority Data:
61/540,943 29.09.2011 US
Title (EN) COMPOUNDS FOR THE TREATMENT OF MYCOBACTERIAL INFECTIONS
(FR) COMPOSÉS POUR LE TRAITEMENT D'INFECTIONS MYCOBACTÉRIENNES
Abstract: front page image
(EN)The invention relates to compounds of Formula (I) or a pharmaceutically acceptable salt, ester or prodrug thereof and further relates to the use of a compound of Formula (I) for the treatment of a bacterial infection, in particular, mycobacterial infection. The compounds of the invention can be used for anti-mycobacterial activity against clinically sensitive as well as resistant strains of Mycobacterium tuberculosis.
(FR)L'invention concerne des composés de formule I ou un sel, un ester ou un promédicament de ceux-ci pharmaceutiquement acceptables; elle concerne également l'utilisation d'un composé de formule I pour le traitement d'une infection bactérienne, en particulier, d'une infection mycobactérienne. Les composés selon l'invention peuvent être utilisés pour une activité anti-mycobactérienne contre des souches cliniquement sensibles et résistantes de Mycobacterium tuberculosis.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)