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Machine translation
1. (WO2013049307) ENHANCED IMMUNE MEMORY DEVELOPMENT BY APTAMER TARGETED MTOR INHIBITION OF T CELLS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2013/049307    International Application No.:    PCT/US2012/057495
Publication Date: 04.04.2013 International Filing Date: 27.09.2012
IPC:
A61K 48/00 (2006.01), C12N 15/11 (2006.01), C07H 21/04 (2006.01)
Applicants: UNIVERSITY OF MIAMI [US/US]; Office of Technology Transfer 1400 NW 10th Avenue, 12th Floor Miami, FL 33136 (US).
GILBOA, Eli [US/US]; (US) (US only)
Inventors: GILBOA, Eli; (US)
Agent: SPRUILL, Murray, W.; Alston & Bird LLP Bank of America Plaza 101 South Tryon Street, Suite 4000 Charlotte, NC 28280-4000 (US)
Priority Data:
61/541,588 30.09.2011 US
Title (EN) ENHANCED IMMUNE MEMORY DEVELOPMENT BY APTAMER TARGETED MTOR INHIBITION OF T CELLS
(FR) DÉVELOPPEMENT D'UNE MÉMOIRE IMMUNITAIRE AMÉLIORÉE PAR UNE INHIBITION DE MTOR DES LYMPHOCYTES T CIBLÉE PAR UN APTAMÈRE
Abstract: front page image
(EN)The disclosure provides compositions for inducing or enhancing immune cell memory. More specifically the compositions provide highly efficient, low toxic and longer lasting protection for treating diseases. The compositions potentiate long-lasting immune memory cells, which are better equipped to provide protective immunity, than the short-lived effector cells generated shortly after vaccination.
(FR)L'invention concerne des compositions pour l'induction ou l'amélioration de la mémoire de cellules immunitaires permettant une protection et un traitement hautement efficaces, faiblement toxiques et à plus longue durée contre une maladie. Les compositions potentialisent des cellules de mémoire immunitaire à longue durée, davantage que les cellules effectrices à courte durée de vie générées rapidement après la vaccination, et sont mieux équipées pour fournir une immunité protectrice.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)