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1. (WO2013048558) METHODS OF THERAPEUTIC MONITORING OF NITROGEN SCAVENGING DRUGS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2013/048558    International Application No.:    PCT/US2012/028620
Publication Date: 04.04.2013 International Filing Date: 09.03.2012
Chapter 2 Demand Filed:    07.12.2012    
IPC:
A61K 49/00 (2006.01)
Applicants: HYPERION THERAPEUTICS, INC. [US/US]; 2000 Sierra Point Parkway, Suite 400 Brisbane, CA 94005 (US)
Inventors: SCHARSCHMIDT, Bruce; (US).
MOKHTARANI, Masoud; (US)
Agent: MORRIS, Patrick D.; Perkins Coie LLP P.O. Box 1208 Seattle, Washington 98111-1208 (US)
Priority Data:
61/542,100 30.09.2011 US
61/564,668 29.11.2011 US
Title (EN) METHODS OF THERAPEUTIC MONITORING OF NITROGEN SCAVENGING DRUGS
(FR) PROCÉDÉS DE SURVEILLANCE THÉRAPEUTIQUE DE MÉDICAMENTS ÉPURATEURS D'AZOTE
Abstract: front page image
(EN)The present disclosure provides methods for evaluating daily ammonia exposure based on a single fasting ammonia blood level measurement, as well as methods that utilize this technique to adjust the dosage of a nitrogen scavenging drug, determine whether to administer a nitrogen scavenging drug, and treat nitrogen retention disorders.
(FR)La présente divulgation concerne des procédés pour évaluer l'exposition quotidienne à l'azote sur base d'une simple mesure à jeun des taux sanguins d'ammoniac, ainsi que des procédés qui utilisent cette technique pour ajuster le dosage d'un médicament épurateur d'azote, pour déterminer l'administration d'un médicament épurateur d'azote et pour traiter les maladies à rétention d'azote.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)