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1. (WO2013047567) CORNEAL EPITHELIAL CELL DEATH INHIBITOR CONTAINING FLAVIN ADENINE DINUCLEOTIDE OR SALT THEREOF AS ACTIVE INGREDIENT
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2013/047567    International Application No.:    PCT/JP2012/074662
Publication Date: 04.04.2013 International Filing Date: 26.09.2012
IPC:
A61K 31/7084 (2006.01), A61K 9/06 (2006.01), A61K 9/08 (2006.01), A61P 27/02 (2006.01), A61P 43/00 (2006.01), C07H 19/207 (2006.01)
Applicants: SANTEN PHARMACEUTICAL CO., LTD. [JP/JP]; 9-19, Shimoshinjo 3-chome, Higashiyodogawa-ku, Osaka-shi, Osaka 5338651 (JP)
Inventors: SAKAMOTO, Asuka; (JP).
NAKAMURA, Masatsugu; (JP)
Agent: FUKAMI PATENT OFFICE, P.C.; Nakanoshima Central Tower, 2-7, Nakanoshima 2-chome, Kita-ku, Osaka-shi, Osaka 5300005 (JP)
Priority Data:
2011-210875 27.09.2011 JP
Title (EN) CORNEAL EPITHELIAL CELL DEATH INHIBITOR CONTAINING FLAVIN ADENINE DINUCLEOTIDE OR SALT THEREOF AS ACTIVE INGREDIENT
(FR) INHIBITEUR DE MORT CELLULAIRE ÉPITHÉLIALE DE LA CORNÉE CONTENANT UN FLAVINE ADÉNINE DINUCLÉOTIDE OU UN SEL DE CELUI-CI COMME PRINCIPE ACTIF
(JA) フラビンアデニンジヌクレオチドまたはその塩を有効成分として含有する角膜上皮細胞死の抑制剤
Abstract: front page image
(EN)Flavin adenine dinucleotide or a salt thereof significantly curbs the decline in viable cell count of corneal epithelial cells induced by ultraviolet radiation, and thus can act as an inhibitor of corneal epithelial cell death induced by ultraviolet radiation.
(FR)L'invention concerne un flavine adénine dinucléotide ou un sel de celui-ci qui refrène de façon significative le déclin du compte de cellules viables de cellules épithéliales de la cornée induit par un rayonnement ultraviolet, et qui peut donc agir comme inhibiteur de la mort cellulaire épithéliale de la cornée induite par un rayonnement ultraviolet.
(JA) フラビンアデニンジヌクレオチドまたはその塩は、紫外線照射によって誘発される角膜上皮細胞の生細胞数の低下を顕著に抑制することから、紫外線照射によって誘発される角膜上皮細胞死の抑制剤となりうる。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)