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1. (WO2013047082) EXOGENOUS OPIOID PEPTIDE-DEGRADING ENZYME
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2013/047082    International Application No.:    PCT/JP2012/072117
Publication Date: 04.04.2013 International Filing Date: 31.08.2012
IPC:
A61K 38/46 (2006.01), A23L 1/305 (2006.01), A61K 35/74 (2006.01), A61P 25/18 (2006.01), A61P 39/02 (2006.01), C12N 9/48 (2006.01), C12N 9/58 (2006.01)
Applicants: AMANO ENZYME INC. [JP/JP]; 2-7, Nishiki 1-chome, Naka-ku, Nagoya-shi, Aichi 4608630 (JP) (For All Designated States Except US).
MATSUBARA Hirotaka [JP/JP]; (JP) (For US Only).
IDO Hiroki [JP/JP]; (JP) (For US Only).
KOIKEDA Satoshi [JP/JP]; (JP) (For US Only)
Inventors: MATSUBARA Hirotaka; (JP).
IDO Hiroki; (JP).
KOIKEDA Satoshi; (JP)
Agent: HAGINO Mikiharu; 1-1, Technoplaza, Kakamigahara-shi, Gifu 5090109 (JP)
Priority Data:
2011-215525 29.09.2011 JP
Title (EN) EXOGENOUS OPIOID PEPTIDE-DEGRADING ENZYME
(FR) ENZYME DE DÉGRADATION D'UN PEPTIDE OPIOÏDE EXOGÈNE
(JA) 外因性オピオイドペプチド分解酵素剤
Abstract: front page image
(EN)The present invention addresses the problem of providing a means for efficiently degrading an exogenous opioid peptide. Provided is an exogenous opioid peptide-degrading enzyme comprising one or more components selected from the group consisting of an enzyme preparation from Penicillin citrinum, an enzyme preparation from Aspergillus oryzae, and an enzyme preparation from Aspergillus meleus, and exhibiting degradation activity against wheat gluten-derived opioid peptides and casein-derived opioid peptides.
(FR)La présente invention aborde le problème de fournir un moyen pour la dégradation efficace d'un peptide opioïde exogène. L'invention concerne une enzyme de dégradation d'un peptide opioïde exogène comprenant un ou plusieurs composants choisis dans le groupe consistant en une préparation enzymatique provenant de Penicillin citrinum, une préparation enzymatique provenant d'Aspergillus oryzae, et une préparation enzymatique provenant d'Aspergillus meleus, et présentant une activité de dégradation contre des peptides opioïdes issus du gluten du blé et des peptides opioïdes issus de la caséine.
(JA) 外因性オピオイドペプチドを効率的に分解する手段を提供することを課題とする。ペニシリウム・シトリヌムからの酵素調製物、アスペルギルス・オリゼからの酵素調製物、アスペルギルス・メレウスからの酵素調製物からなる群より選択される一以上の成分を含み、小麦グルテン由来のオピオイドペプチド及びカゼイン由来のオピオイドペプチドに対する分解活性を示す、外因性オピオイドペプチド分解酵素剤が提供される。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)