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1. (WO2013045891) A PHARMACEUTICAL COMPOSITION COMPRISING THE PHYTOCANNABINOIDS CANNABIDIVARIN (CBDV) AND CANNABIDIOL (CBD)
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2013/045891    International Application No.:    PCT/GB2012/052284
Publication Date: 04.04.2013 International Filing Date: 14.09.2012
Chapter 2 Demand Filed:    29.07.2013    
IPC:
A61K 31/05 (2006.01), A61K 31/352 (2006.01), A61K 36/185 (2006.01), A61K 45/06 (2006.01), A61P 25/08 (2006.01)
Applicants: GW PHARMA LIMITED [GB/GB]; Porton Down Science Park Salisbury Wiltshire SP4 0JQ (GB) (For All Designated States Except US).
OTSUKA PHARMACEUTICAL CO., LIMITED [JP/JP]; 9, Kanda-Tsukasamachi 2-Chome, Chiyoda-Ku Tokyo, 101-8535 (JP) (For All Designated States Except US).
WHALLEY, Benjamin [GB/GB]; (GB) (For US Only).
WILLIAMS, Claire [GB/GB]; (GB) (For US Only).
STEPHENS, Gary [GB/GB]; (GB) (For US Only)
Inventors: WHALLEY, Benjamin; (GB).
WILLIAMS, Claire; (GB).
STEPHENS, Gary; (GB)
Agent: HARRISON GODDARD FOOTE; 4th Floor, Merchant Exchange 17-19 Whitworth Street West Manchester M1 5WG (GB)
Priority Data:
1116789.7 29.09.2011 GB
Title (EN) A PHARMACEUTICAL COMPOSITION COMPRISING THE PHYTOCANNABINOIDS CANNABIDIVARIN (CBDV) AND CANNABIDIOL (CBD)
(FR) COMPOSITION PHARMACEUTIQUE COMPRENANT LES PHYTOCANNABINOÏDES CANNABIDIVARINE (CBDV) ET CANNABIDIOL (CBD)
Abstract: front page image
(EN)This invention relates to a pharmaceutical composition comprising or consisting essentially of the phytocannabinoids cannabidivarin (CBDV)and cannabidiol (CBD). The composition is particularly safe and efficacious for use in the treatment of neurological conditions, characterized by hyper-excitability of the central nervous system, convulsions or seizures such as occur in epilepsy. Preferably the CBDV and the CBD are present with at least one non- cannabinoid component of cannabis such as one or more terpenes or a terpene fraction. More particularly the composition further comprises one or more cannabichromene type compounds. Particularly cannabichromene propyl variant (CBCV) and / or cannabichromene (CBC).More particularly still the composition is absent or substantially absent of other cannabinoids, including in particular tetrahydrocannabinol (THC) and tetrahydrocannabivarin (THCV), which would normally be present in significant amounts in cannabis chemotypes bred to contain a significant amount of CBDV and / or CBD.
(FR)Cette invention porte sur une composition pharmaceutique comprenant les phytocannabinoïdes cannabidivarine (CBDV) et cannabidiol (CBD) ou essentiellement constituée de ceux-ci. La composition est particulièrement sans danger et efficace pour être utilisée dans le traitement d'affections neurologiques, caractérisées par une hyperexcitabilité du système nerveux central, des convulsions ou des crises épileptiques telles que celles qui surviennent dans l'épilepsie. De préférence la CBDV et le CBD comportent au moins un composant non-cannabinoïde du cannabis tel qu'un ou plusieurs terpènes ou une fraction terpénique. Plus particulièrement, la composition comprend en outre un ou plusieurs composés de type cannabichromène, en particulier le variant propylique du cannabichromène (CBCV) et/ou le cannabichromène (CBC). Plus particulièrement encore, la composition est exempte ou pratiquement exempte d'autres cannabinoïdes, notamment en particulier de tétrahydrocannabinol (THC) et de tétrahydrocannabivarine (THCV), qui seraient normalement présents en quantités importantes dans des chimiotypes du cannabis sélectionnés pour contenir une quantité importante de CBDV et/ou de CBD.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)