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1. (WO2013045707) BIOLOGICAL MATERIALS RELATED TO C-MET
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2013/045707    International Application No.:    PCT/EP2012/069373
Publication Date: 04.04.2013 International Filing Date: 01.10.2012
IPC:
A61K 39/395 (2006.01), A61P 35/00 (2006.01), C07K 16/18 (2006.01), C07K 16/28 (2006.01)
Applicants: ABLYNX NV [BE/BE]; Technologiepark 21 B-9052 Ghent-Zwijnaarde (BE)
Inventors: BESTE, Gerald; (BE).
HERMANS, Guy; (BE).
STEFFENSEN, Soren; (BE).
SZYROKI, Alexander; (DE).
VERVERKEN, Cedric Jozef Néotère; (BE).
DENAYER, Tinneke; (BE)
Agent: TAORMINO, Joseph; Hoffmann · Eitle Arabellastrasse 4 81925 München (DE)
Priority Data:
61/541,368 30.09.2011 US
13/435,567 30.03.2012 US
Title (EN) BIOLOGICAL MATERIALS RELATED TO C-MET
(FR) SUBSTANCES BIOLOGIQUES LIÉES À C-MET
Abstract: front page image
(EN)The present invention relates to biological materials related to c-Met possibly in combination with VEGF and/or EGFR, and more in particular to polypeptides, nucleic acids encoding such polypeptides; to methods for preparing such polypeptides; to host cells expressing or capable of expressing such polypeptides; to compositions and in particular to pharmaceutical compositions that comprise such polypeptides, for prophylactic, therapeutic or diagnostic purposes. Methods and kits for assessing the responsiveness of a patient to c-Met therapy are also described and provided.
(FR)La présente invention concerne des substances biologiques liées à c-Met, éventuellement en combinaison avec VEGF et/ou EGFR, et plus particulièrement des polypeptides, des acides nucléiques codant ces polypeptides; des procédés de préparation de ces polypeptides; des cellules hôtes exprimant ou capables d'exprimer ces polypeptides; des compositions et en particulier des compositions pharmaceutiques comprenant de tels polypeptides, à des fins prophylactiques, thérapeutiques ou de diagnostic. L'invention concerne également des procédés et des kits permettant d'évaluer la réactivité d'un patient à la thérapie c-Met.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)