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1. (WO2013045662) PEPTIDE MARGIN IMAGING AGENTS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2013/045662    International Application No.:    PCT/EP2012/069265
Publication Date: 04.04.2013 International Filing Date: 28.09.2012
IPC:
A61K 49/00 (2006.01)
Applicants: GE HEALTHCARE AS [NO/NO]; P.O. Box 4220 Nydalen Nycoveien 1-2 N-0401 Oslo (NO)
Inventors: HEALEY, Andrew; (NO).
TORHEIM, Geir; (NO).
BENDIKSEN, Ragnar; (NO).
DALSGAARD, Grethe, Tang; (GB).
JOHANNESEN, Edvin, Wilhelm; (NO).
BJERKE, Roger; (NO)
Agent: CANNING, Lewis; GE Healthcare Limited Pollards Wood Nightingales Lane Chalfont St Giles Buckinghamshire HP8 4SP (GB)
Priority Data:
1116733.5 28.09.2011 GB
Title (EN) PEPTIDE MARGIN IMAGING AGENTS
(FR) AGENTS PEPTIDIQUES D'IMAGERIE DE MARGES
Abstract: front page image
(EN)The present invention relates to labelled c-Met binding peptides suitable for optical imaging of tumour margins in vivo. The peptides are labelled with an optical reporter group suitable for imaging in the red to near-infrared region. Also disclosed are in vivo imaging methods, especially of use in the diagnosis of cancer and imaging of tumour margins during surgical resection.
(FR)L'invention concerne des peptides marqués se liant à c-Met, qui conviennent pour l'imagerie optique de marges de tumeur in vivo. Ces peptides sont marqués à l'aide d'un groupe rapporteur optique qui convient pour produire une imagerie dans la région comprise entre le rouge et l'infrarouge proche. L'invention concerne aussi des procédés d'imagerie in vivo qui s'utilisent notamment dans le diagnostic du cancer et l'imagerie de marges de tumeur, pendant une résection chirurgicale.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)