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1. (WO2013045053) EVALUATION CIRCUIT FOR AN OPTOELECTRONIC DETECTOR AND METHOD FOR RECORDING FLUORESCENCE EVENTS

Pub. No.:    WO/2013/045053    International Application No.:    PCT/EP2012/003939
Publication Date: Apr 4, 2013 International Filing Date: Sep 20, 2012
IPC: G01N 21/64
G02B 21/00
G01J 3/28
G01J 3/44
Applicants: CARL ZEISS MICROSCOPY GMBH
MÖHLER, Gunter
SCHMIDT, Dietmar
HOLUB, Oliver
HAUSCHILD, Robert
Inventors: MÖHLER, Gunter
SCHMIDT, Dietmar
HOLUB, Oliver
HAUSCHILD, Robert
Title: EVALUATION CIRCUIT FOR AN OPTOELECTRONIC DETECTOR AND METHOD FOR RECORDING FLUORESCENCE EVENTS
Abstract:
1. An evaluation circuit for an optoelectronic detector and method for recording fluorescence events. 2.1 In fluorescence measurements and measurements of the Raman spectrum using pulsed stimulation, spectrally overlapping stray light and fluorescent light interfere with each other, reducing the sensitivity of the measurements. With known evaluation circuits (1), which provide synchronisation of an analogue/digital converter (2) with the light pulses, it is only possible for fluorescent light to be absorbed, or else fluorescent and stray light cannot be differentiated. An improved evaluation circuit (1) is required that provides high sensitivity for low expense. 2.2 For this purpose, a shift register (3) having at least one data input, one clock input, a plurality of register stages and at least one data output is provided, wherein the output from the analogue/digital converter (2) is connected to the data input to the shift register (3). With a shift register, fluorescent and stray light can be differentiated temporally at low expense. 2.3 Microscopy