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1. WO2013040648 - PNEUMOCOCCAL GLPO IMMUNOGEN

Publication Number WO/2013/040648
Publication Date 28.03.2013
International Application No. PCT/AU2012/001139
International Filing Date 21.09.2012
IPC
A61K 38/44 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
43Enzymes; Proenzymes; Derivatives thereof
44Oxidoreductases (1)
A61K 38/02 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
02Peptides of undefined number of amino acids; Derivatives thereof
A61K 39/40 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
40bacterial
A61P 31/04 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
04Antibacterial agents
CPC
A61K 38/443
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
43Enzymes; Proenzymes; Derivatives thereof
44Oxidoreductases (1)
443acting on CH-OH groups as donors, e.g. glucose oxidase, lactate dehydrogenase (1.1)
A61K 39/092
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
02Bacterial antigens
09Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus; , streptococcus
092Streptococcus
A61P 31/04
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
04Antibacterial agents
C12N 9/0006
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
9Enzymes; Proenzymes; Compositions thereof
0004Oxidoreductases (1.)
0006acting on CH-OH groups as donors (1.1)
C12Y 101/03021
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
YENZYMES
101Oxidoreductases acting on the CH-OH group of donors (1.1)
03with a oxygen as acceptor (1.1.3)
03021Glycerol-3-phosphate-oxidase (1.1.3.21)
Y02A 50/30
YSECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
50in human health protection
30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Applicants
  • ADELAIDE RESEARCH & INNOVATION PTY LTD [AU]/[AU] (AllExceptUS)
  • PATON, James [AU]/[AU] (US)
  • MAHDI, Layla [AU]/[AU] (US)
  • OGUNNIYI, Abiodun [AU]/[AU] (US)
Inventors
  • PATON, James
  • MAHDI, Layla
  • OGUNNIYI, Abiodun
Agents
  • A.P.T. Patent and Trade Mark Attorneys
Priority Data
201190393023.09.2011AU
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) PNEUMOCOCCAL GLPO IMMUNOGEN
(FR) IMMUNOGÈNE GLPO PNEUMOCOCCIQUE
Abstract
(EN)
An immunogenic composition, that may be a vaccine comprising GlpO or a fragment thereof suitable for use in the treatment or prevention of a streptococcal infection, in particular meningitis. The GlpO or fragment thereof is preferably enzymatically inactive. In a preferred form immunogenic comprises additionally a further immunogen known to be protective against steptococcal infection which further immunogen is preferably a protein. One particularly illustrated such further protein is a non-toxic pneumolysin.
(FR)
L'invention concerne une composition immunogène qui peut être un vaccin comprenant GlpO ou un fragment de celui-ci, approprié pour l'utilisation dans le traitement ou la prévention d'une infection streptococcique, en particulier une méningite. Le GlpO ou le fragment de celui-ci est de préférence inactif du point de vue enzymatique. Dans une forme préférée, la composition immunogène comprend en outre un immunogène supplémentaire connu comme étant protecteur contre une infection streptococcique, ledit immunogène supplémentaire étant de préférence une protéine. Une telle protéine supplémentaire particulièrement illustrée est une pneumolysine non toxique.
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