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1. (WO2013026099) FN14 BINDING PROTEINS AND USES THEREOF
Latest bibliographic data on file with the International Bureau   
Pub. No.: WO/2013/026099 International Application No.: PCT/AU2012/000989
Publication Date: 28.02.2013 International Filing Date: 23.08.2012
IPC:
C07K 16/30 (2006.01) ,A61K 39/395 (2006.01) ,A61P 21/00 (2006.01) ,A61P 35/00 (2006.01) ,A61P 3/10 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18
against material from animals or humans
28
against receptors, cell surface antigens or cell surface determinants
30
from tumour cells
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
395
Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
21
Drugs for disorders of the muscular or neuromuscular system
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3
Drugs for disorders of the metabolism
08
for glucose homeostasis
10
for hyperglycaemia, e.g. antidiabetics
Applicants:
HOOGENRAAD, Nicholas Johannes [AU/AU]; AU (UsOnly)
JOHNSTON, Amelia Jane [AU/AU]; AU (UsOnly)
SILKE, John [GB/AU]; AU (UsOnly)
TRANSBIO LTD [AU/AU]; Technology Enterprise Centre La Trobe University R&D Park 2 Research Avenue Bundoora, Victoria 3083, AU (AllExceptUS)
Inventors:
HOOGENRAAD, Nicholas Johannes; AU
JOHNSTON, Amelia Jane; AU
SILKE, John; AU
Agent:
FB RICE; Level 23, 200 Queen Street Melbourne, Victoria 3000, AU
Priority Data:
61/526,59923.08.2011US
Title (EN) FN14 BINDING PROTEINS AND USES THEREOF
(FR) PROTÉINES DE LIAISON À FN14 ET LEURS UTILISATIONS
Abstract:
(EN) The present disclosure provides proteins comprising antibody antigen binding domains that bind to Fn14 and uses thereof. The present disclosure also provides methods for treating wasting disorders, such as cachexia.
(FR) La présente invention concerne des protéines comprenant des domaines de liaison à un antigène d'un anticorps, qui se lient à Fn14, et leurs utilisations. La présente invention concerne également des méthodes de traitement de troubles cachectiques, tels que la cachexie.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)