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1. (WO2013022996) THE UTILITY OF NEMATODE SMALL MOLECULES
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2013/022996 International Application No.: PCT/US2012/050031
Publication Date: 14.02.2013 International Filing Date: 08.08.2012
IPC:
A61K 31/7052 (2006.01) ,A61K 31/70 (2006.01) ,A61K 31/404 (2006.01) ,A61K 31/35 (2006.01) ,A61P 29/00 (2006.01) ,A61P 37/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
70
Carbohydrates; Sugars; Derivatives thereof
7042
Compounds having saccharide radicals and heterocyclic rings
7052
having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
70
Carbohydrates; Sugars; Derivatives thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
40
having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
403
condensed with carbocyclic rings, e.g. carbazole
404
Indoles, e.g. pindolol
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
335
having oxygen as the only ring hetero atom, e.g. fungichromin
35
having six-membered rings with one oxygen as the only ring hetero atom
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
29
Non-central analgesic, antipyretic or antiinflammatory agents, e.g antirheumatic agents; Non-steroidal antiinflammatory drugs (NSAIDs)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
37
Drugs for immunological or allergic disorders
Applicants:
CHOE, Andrea [US/US]; US (UsOnly)
STERNBERG, Paul Warren [US/US]; US (UsOnly)
SCHROEDER, Frank Clemens [DE/US]; US (UsOnly)
VON REUSS, Stephan Heinrich [DE/US]; US (UsOnly)
CALIFORNIA INSTITUTE OF TECHNOLOGY [US/US]; 1200 East California Boulevard Pasadena, California 91125, US (AllExceptUS)
BOYCE THOMPSON INSTITUTE FOR PLANT RESEARCH [US/US]; Tower Road Ithaca, New York 14853, US (AllExceptUS)
Inventors:
CHOE, Andrea; US
STERNBERG, Paul Warren; US
SCHROEDER, Frank Clemens; US
VON REUSS, Stephan Heinrich; US
Agent:
SENN, Sean; Nixon Peabody LLP Gas Company Tower 555 West Fifth Street 46th Floor Los Angeles, California 90013, US
Priority Data:
61/521,29508.08.2011US
61/620,33104.04.2012US
61/620,34304.04.2012US
61/620,34804.04.2012US
Title (EN) THE UTILITY OF NEMATODE SMALL MOLECULES
(FR) UTILITÉ DE NÉMATODES À PETITES MOLÉCULES
Abstract:
(EN) The present invention relates to methods of treating immune disorders and/or inflammation using certain modulator compounds. In one embodiment, the present invention provides a method of treating an immune and inflammatory disorders disorder by administering a composition comprising a therapeutically effective dosage of an ascaroside compound, or a mixture of ascaroside compounds, or a mixture containing at least one ascaroside..
(FR) La présente invention concerne des procédés de traitement de troubles immunitaires et/ou inflammatoires utilisant certains composés modulateurs. Selon un mode de réalisation, la présente invention concerne un procédé de traitement d'un trouble immunitaire et inflammatoire par administration d'une composition comprenant une dose thérapeutiquement efficace d'un composé d'ascaroside, ou un mélange de composés d'ascaroside, ou un mélange contenant au moins un ascaroside.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)