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1. WO2013022996 - THE UTILITY OF NEMATODE SMALL MOLECULES

Publication Number WO/2013/022996
Publication Date 14.02.2013
International Application No. PCT/US2012/050031
International Filing Date 08.08.2012
IPC
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
70
Carbohydrates; Sugars; Derivatives thereof
7042
Compounds having saccharide radicals and heterocyclic rings
7052
having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
70
Carbohydrates; Sugars; Derivatives thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
40
having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
403
condensed with carbocyclic rings, e.g. carbazole
404
Indoles, e.g. pindolol
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
335
having oxygen as the only ring hetero atom, e.g. fungichromin
35
having six-membered rings with one oxygen as the only ring hetero atom
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
29
Non-central analgesic, antipyretic or antiinflammatory agents, e.g antirheumatic agents; Non-steroidal antiinflammatory drugs (NSAIDs)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
37
Drugs for immunological or allergic disorders
A61K 31/7052 (2006.01)
A61K 31/70 (2006.01)
A61K 31/404 (2006.01)
A61K 31/35 (2006.01)
A61P 29/00 (2006.01)
A61P 37/00 (2006.01)
CPC
A01N 37/36
A01N 43/16
A01N 43/38
A01N 63/10
A61K 31/454
A61K 31/7028
Applicants
  • CALIFORNIA INSTITUTE OF TECHNOLOGY [US/US]; 1200 East California Boulevard Pasadena, California 91125, US (AllExceptUS)
  • BOYCE THOMPSON INSTITUTE FOR PLANT RESEARCH [US/US]; Tower Road Ithaca, New York 14853, US (AllExceptUS)
  • CHOE, Andrea [US/US]; US (UsOnly)
  • STERNBERG, Paul Warren [US/US]; US (UsOnly)
  • SCHROEDER, Frank Clemens [DE/US]; US (UsOnly)
  • VON REUSS, Stephan Heinrich [DE/US]; US (UsOnly)
Inventors
  • CHOE, Andrea; US
  • STERNBERG, Paul Warren; US
  • SCHROEDER, Frank Clemens; US
  • VON REUSS, Stephan Heinrich; US
Agents
  • SENN, Sean; Nixon Peabody LLP Gas Company Tower 555 West Fifth Street 46th Floor Los Angeles, California 90013, US
Priority Data
61/521,29508.08.2011US
61/620,33104.04.2012US
61/620,34304.04.2012US
61/620,34804.04.2012US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) THE UTILITY OF NEMATODE SMALL MOLECULES
(FR) UTILITÉ DE NÉMATODES À PETITES MOLÉCULES
Abstract
(EN)
The present invention relates to methods of treating immune disorders and/or inflammation using certain modulator compounds. In one embodiment, the present invention provides a method of treating an immune and inflammatory disorders disorder by administering a composition comprising a therapeutically effective dosage of an ascaroside compound, or a mixture of ascaroside compounds, or a mixture containing at least one ascaroside..
(FR)
La présente invention concerne des procédés de traitement de troubles immunitaires et/ou inflammatoires utilisant certains composés modulateurs. Selon un mode de réalisation, la présente invention concerne un procédé de traitement d'un trouble immunitaire et inflammatoire par administration d'une composition comprenant une dose thérapeutiquement efficace d'un composé d'ascaroside, ou un mélange de composés d'ascaroside, ou un mélange contenant au moins un ascaroside.
Also published as
Latest bibliographic data on file with the International Bureau