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Machine translation
2. (WO2013016661) METHOD FOR INHIBITING TRYPANSOMA CRUZI
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2013/016661    International Application No.:    PCT/US2012/048616
Publication Date: 31.01.2013 International Filing Date: 27.07.2012
IPC:
A61K 31/122 (2006.01)
Applicants: HOWARD UNIVERSITY [US/US]; 2400 Sixth Street NW Suite 321 Washington, District of Columbia 20059 (US) (For All Designated States Except US).
BAKARE, Oladapo [US/US]; (US) (For US Only).
LEE, Clarence, M. [US/US]; (US) (For US Only).
BRANDY, Yajkini [US/US]; (US) (For US Only).
KHRAIWESH, Mozna, Husein [JO/US]; (US) (For US Only)
Inventors: BAKARE, Oladapo; (US).
LEE, Clarence, M.; (US).
BRANDY, Yajkini; (US).
KHRAIWESH, Mozna, Husein; (US)
Agent: KRATZ, Rudy; Fitch, Even, Tabin & Flannery 120 S. LaSalle Street Suite 1600 Chicago, Illinois 60603 (US)
Priority Data:
61/512,232 27.07.2011 US
Title (EN) METHOD FOR INHIBITING TRYPANSOMA CRUZI
(FR) PROCÉDÉ D'INHIBITION DE TRYPANSOMA CRUZI
Abstract: front page image
(EN)In its broadest aspect, a method for treating a mammalian patient at risk or suffering from a disease caused by a kinetoplastid parasite comprises administering to such subject an effective kinetoplasticidal amount of an imido-substituted 1,4- naphthoquinone to inhibit the kinetoplastid. In an important aspect, a method of inhibiting Trypanosoma cruzi comprises administering to a patient for prophylaxis or to a patient in need of treatment an antitrypanosomal effective amount of an imido-substituted 1 A-naphthoquinone.
(FR)La présente invention concerne, dans sa plus large portée, une méthode de traitement d'un patient mammifère risquant de souffrir ou souffrant d'une maladie provoquée par le parasite cinétoplastide. Ladite méthode comprend l'administration audit sujet d'une quantité cinétoplasticide d'une 1,4-naphtoquinone imido-substituée efficace pour inhiber le cinétoplastide. Dans un aspect majeur, l'invention porte sur un procédé d'inhibition de Trypanosoma cruzi, comprenant l'administration à un patient dans un but prophylactique, ou à un patient ayant besoin d'un traitement, d'une quantité efficace antitrypanosomale d'une 1,4-naphtoquinone imido-substituée.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)