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1. (WO2013014660) INDANE DIMERS FOR USE IN THE TREATMENT OF AUTOIMMUNE INFLAMMATORY DISEASE

Pub. No.:    WO/2013/014660    International Application No.:    PCT/IE2012/000038
Publication Date: Fri Feb 01 00:59:59 CET 2013 International Filing Date: Sat Jul 21 01:59:59 CEST 2012
IPC: C07C 65/19
C07C 69/76
C07C 229/08
C07C 235/42
A61K 31/166
A61K 31/167
A61K 31/192
A61K 31/205
A61K 31/235
A61P 29/00
Applicants: VENANTIUS LIMITED
SHERIDAN, Helen
FRANKISH, Neil
Inventors: SHERIDAN, Helen
FRANKISH, Neil
Title: INDANE DIMERS FOR USE IN THE TREATMENT OF AUTOIMMUNE INFLAMMATORY DISEASE
Abstract:
Compounds particularly for use in an autoimmune inflammatory disease and especially the treatment of inflammatory bowel disease have the formula: wherein R is selected from one or more of the same or different of hydrogen, hydroxyl, optionally substituted alkyl, optionally substituted aryl, alkoxy, aryloxy, thiol, and optionally substituted amino, and wherein R1 is selected from one or more of the same or different of hydrogen, acetyl, optionally substituted alkyl, optionally substituted aryl, and an amino acid selected from leucine, valine, isoleucine, and glycine.