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1. WO2013009717 - VIRION DERIVED PROTEIN NANOPARTICLES FOR DELIVERING DIAGNOSTIC OR THERAPEUTIC AGENTS FOR THE TREATMENT OF SKIN-RELATED DISEASES

Publication Number WO/2013/009717
Publication Date 17.01.2013
International Application No. PCT/US2012/045989
International Filing Date 09.07.2012
IPC
A61P 17/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
17Drugs for dermatological disorders
C12N 15/86 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
79Vectors or expression systems specially adapted for eukaryotic hosts
85for animal cells
86Viral vectors
CPC
A61P 17/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
17Drugs for dermatological disorders
C12N 15/86
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
79Vectors or expression systems specially adapted for eukaryotic hosts
85for animal cells
86Viral vectors
C12N 2710/16641
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
2710dsDNA Viruses
00011dsDNA Viruses
16011Herpesviridae
16611Simplexvirus, e.g. human herpesvirus 1, 2
16641Use of virus, viral particle or viral elements as a vector
C12N 2710/20041
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
2710dsDNA Viruses
00011dsDNA Viruses
20011Papillomaviridae
20041Use of virus, viral particle or viral elements as a vector
C12N 2710/20042
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
2710dsDNA Viruses
00011dsDNA Viruses
20011Papillomaviridae
20041Use of virus, viral particle or viral elements as a vector
20042virus or viral particle as vehicle, e.g. encapsulating small organic molecule
Applicants
  • DE LOS PINOS, Elisabet [ES]/[US]
Inventors
  • DE LOS PINOS, Elisabet
Agents
  • KERNER, Herbert
Priority Data
13/221,80330.08.2011US
13/253,02804.10.2011US
61/506,14010.07.2011US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) VIRION DERIVED PROTEIN NANOPARTICLES FOR DELIVERING DIAGNOSTIC OR THERAPEUTIC AGENTS FOR THE TREATMENT OF SKIN-RELATED DISEASES
(FR) NANOPARTICULES DE PROTÉINE VIRIONIQUE POUR L'ADMINISTRATION D'AGENTS DIAGNOSTIQUES OU THÉRAPEUTIQUES POUR LE TRAITEMENT DE MALADIES CUTANÉES
Abstract
(EN)
This invention relates to a transdermal delivery system for treating skin-related diseases employing papilloma-derived protein nanoparticles to deliver drugs to the keratinocytes and basal membrane cells for the treatment of skin-related diseases. The current invention presents an effective method for delivering small molecule nucleic acids to the epidermal cells.
(FR)
La présente invention a pour objet un système d'administration transdermique pour le traitement de maladies cutanées utilisant des nanoparticules de protéine dérivée du papillome pour administrer des médicaments aux kératinocytes et aux cellules de la membrane basale pour le traitement de maladies cutanées. La présente invention concerne une méthode efficace pour administrer de petites molécules d'acides nucléiques aux cellules épidermiques.
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