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1. WO2013007052 - FULLY HUMAN ANTIBODIES AGAINST HUMAN CD20

Publication Number WO/2013/007052
Publication Date 17.01.2013
International Application No. PCT/CN2011/078190
International Filing Date 10.08.2011
IPC
C07K 16/18 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
A61K 39/395 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
A61P 35/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
A61P 37/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
37Drugs for immunological or allergic disorders
CPC
A61K 2039/505
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
505comprising antibodies
A61P 35/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
A61P 35/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
02specific for leukemia
A61P 37/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
37Drugs for immunological or allergic disorders
C07K 16/2887
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
28against receptors, cell surface antigens or cell surface determinants
2887against CD20
C07K 2317/21
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
2317Immunoglobulins specific features
20characterized by taxonomic origin
21from primates, e.g. man
Applicants
  • LIU, Qingfa [CN]/[CN]
Inventors
  • LIU, Qingfa
Agents
  • J.Z.M.C. PATENT AND TRADEMARK LAW OFFICE
Priority Data
201110196255.613.07.2011CN
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) FULLY HUMAN ANTIBODIES AGAINST HUMAN CD20
(FR) ANTICORPS ENTIÈREMENT HUMAINS CONTRE CD20 HUMAIN
Abstract
(EN)
The present invention discloses anti human CD20 (hCD20) monoclonal antibodies and nucleic acid sequences encoding them. Preferably, the anti hCD20 antibodies of the present invention comprise fully human light and/or heavy chain variable regions derived from molecular evolution. Also disclosed are potentiality of pharmaceutical compositions comprising the human antibodies in human disease treatment and therapeutic methods for using the human antibodies.
(FR)
La présente invention concerne des anticorps monoclonaux anti-CD20 humain (hCD20) et des séquences d'acides nucléiques codant pour ceux-ci. De préférence, les anticorps anti-hCD20 de la présente invention comprennent des régions variables à chaîne légère et/ou lourde entièrement humaines dérivées de l'évolution moléculaire. L'invention concerne également la potentialité de compositions pharmaceutiques comprenant les anticorps humains dans le traitement de maladies humaines et des procédés thérapeutiques d'utilisation des anticorps humains.
Also published as
Latest bibliographic data on file with the International Bureau